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Natural Polyphenols for Prevention and Treatment of Cancer

There is much epidemiological evidence that a diet rich in fruits and vegetables could lower the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols. Besides, numerous studies have demonstrated that natural polyphenols could be used for the prevention and treatme...

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Autores principales: Zhou, Yue, Zheng, Jie, Li, Ya, Xu, Dong-Ping, Li, Sha, Chen, Yu-Ming, Li, Hua-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997428/
https://www.ncbi.nlm.nih.gov/pubmed/27556486
http://dx.doi.org/10.3390/nu8080515
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author Zhou, Yue
Zheng, Jie
Li, Ya
Xu, Dong-Ping
Li, Sha
Chen, Yu-Ming
Li, Hua-Bin
author_facet Zhou, Yue
Zheng, Jie
Li, Ya
Xu, Dong-Ping
Li, Sha
Chen, Yu-Ming
Li, Hua-Bin
author_sort Zhou, Yue
collection PubMed
description There is much epidemiological evidence that a diet rich in fruits and vegetables could lower the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols. Besides, numerous studies have demonstrated that natural polyphenols could be used for the prevention and treatment of cancer. Potential mechanisms included antioxidant, anti-inflammation as well as the modulation of multiple molecular events involved in carcinogenesis. The current review summarized the anticancer efficacy of major polyphenol classes (flavonoids, phenolic acids, lignans and stilbenes) and discussed the potential mechanisms of action, which were based on epidemiological, in vitro, in vivo and clinical studies within the past five years.
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spelling pubmed-49974282016-08-26 Natural Polyphenols for Prevention and Treatment of Cancer Zhou, Yue Zheng, Jie Li, Ya Xu, Dong-Ping Li, Sha Chen, Yu-Ming Li, Hua-Bin Nutrients Review There is much epidemiological evidence that a diet rich in fruits and vegetables could lower the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols. Besides, numerous studies have demonstrated that natural polyphenols could be used for the prevention and treatment of cancer. Potential mechanisms included antioxidant, anti-inflammation as well as the modulation of multiple molecular events involved in carcinogenesis. The current review summarized the anticancer efficacy of major polyphenol classes (flavonoids, phenolic acids, lignans and stilbenes) and discussed the potential mechanisms of action, which were based on epidemiological, in vitro, in vivo and clinical studies within the past five years. MDPI 2016-08-22 /pmc/articles/PMC4997428/ /pubmed/27556486 http://dx.doi.org/10.3390/nu8080515 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhou, Yue
Zheng, Jie
Li, Ya
Xu, Dong-Ping
Li, Sha
Chen, Yu-Ming
Li, Hua-Bin
Natural Polyphenols for Prevention and Treatment of Cancer
title Natural Polyphenols for Prevention and Treatment of Cancer
title_full Natural Polyphenols for Prevention and Treatment of Cancer
title_fullStr Natural Polyphenols for Prevention and Treatment of Cancer
title_full_unstemmed Natural Polyphenols for Prevention and Treatment of Cancer
title_short Natural Polyphenols for Prevention and Treatment of Cancer
title_sort natural polyphenols for prevention and treatment of cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997428/
https://www.ncbi.nlm.nih.gov/pubmed/27556486
http://dx.doi.org/10.3390/nu8080515
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