Genetic Variations in the Promoter of the APE1 Gene Are Associated with DMF-Induced Abnormal Liver Function: A Case-Control Study in a Chinese Population

Acute or long-term exposure to N,N-dimethylformamide (DMF) can induce abnormal liver function. It is well known that DMF is mainly metabolized in the liver and thereby produces reactive oxygen species (ROS). The base excision repair (BER) pathway is regarded as a very important pathway involved in r...

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Detalles Bibliográficos
Autores principales: Tong, Zhimin, Shen, Huanxi, Yang, Dandan, Zhang, Feng, Bai, Ying, Li, Qian, Shi, Jian, Zhang, Hengdong, Zhu, Baoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997438/
https://www.ncbi.nlm.nih.gov/pubmed/27463724
http://dx.doi.org/10.3390/ijerph13080752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997438/
https://www.ncbi.nlm.nih.gov/pubmed/27463724
http://dx.doi.org/10.3390/ijerph13080752

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