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Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China

Objective: The aims of the study were to investigate the prevalence of pre-diabetes and explore its associated risk factors in rural areas of Ningbo, China. Methods: A cross-sectional survey was conducted with 4583 adult residents in rural areas of Ningbo, China between March and May 2013. The surve...

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Autores principales: Zhao, Ming, Lin, Hongbo, Yuan, Yanyan, Wang, Fuyan, Xi, Yang, Wen, Li Ming, Shen, Peng, Bu, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997494/
https://www.ncbi.nlm.nih.gov/pubmed/27517947
http://dx.doi.org/10.3390/ijerph13080808
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author Zhao, Ming
Lin, Hongbo
Yuan, Yanyan
Wang, Fuyan
Xi, Yang
Wen, Li Ming
Shen, Peng
Bu, Shizhong
author_facet Zhao, Ming
Lin, Hongbo
Yuan, Yanyan
Wang, Fuyan
Xi, Yang
Wen, Li Ming
Shen, Peng
Bu, Shizhong
author_sort Zhao, Ming
collection PubMed
description Objective: The aims of the study were to investigate the prevalence of pre-diabetes and explore its associated risk factors in rural areas of Ningbo, China. Methods: A cross-sectional survey was conducted with 4583 adult residents in rural areas of Ningbo, China between March and May 2013. The survey used a multi-stage, stratified, cluster sampling method. Data collected included demographics and medical history, anthropometric measurements, blood pressure, blood lipid, and plasma glucose. After at least 10 h of overnight fasting, participants underwent an oral glucose tolerance test (OGTT) to identify pre-diabetes. Univariate and multivariate logistic regression analyses were used to evaluate the associated risk factors for pre-diabetes, and to estimate the effect of interaction between the factors. Results: There were 1307 survey participants having pre-diabetes (28.52%) and the age-standardized prevalence was 30.53%. Multivariate logistic regression results showed that overweight/obesity, hypertension, and higher triglycerides were the risk factors for developing pre-diabetes. There were positive interactions between overweight/obesity and triglycerides, and also between hypertension and triglycerides on the multiplicative scale, suggesting that they synergistically influenced the development of pre-diabetes. Conclusions: The rural areas in Ningbo had a high prevalence of pre-diabetes. Overweight and obesity, hypertension, and elevated triglycerides were the major risk factors. There is a need of early intervention for preventing pre-diabetes.
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spelling pubmed-49974942016-08-26 Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China Zhao, Ming Lin, Hongbo Yuan, Yanyan Wang, Fuyan Xi, Yang Wen, Li Ming Shen, Peng Bu, Shizhong Int J Environ Res Public Health Article Objective: The aims of the study were to investigate the prevalence of pre-diabetes and explore its associated risk factors in rural areas of Ningbo, China. Methods: A cross-sectional survey was conducted with 4583 adult residents in rural areas of Ningbo, China between March and May 2013. The survey used a multi-stage, stratified, cluster sampling method. Data collected included demographics and medical history, anthropometric measurements, blood pressure, blood lipid, and plasma glucose. After at least 10 h of overnight fasting, participants underwent an oral glucose tolerance test (OGTT) to identify pre-diabetes. Univariate and multivariate logistic regression analyses were used to evaluate the associated risk factors for pre-diabetes, and to estimate the effect of interaction between the factors. Results: There were 1307 survey participants having pre-diabetes (28.52%) and the age-standardized prevalence was 30.53%. Multivariate logistic regression results showed that overweight/obesity, hypertension, and higher triglycerides were the risk factors for developing pre-diabetes. There were positive interactions between overweight/obesity and triglycerides, and also between hypertension and triglycerides on the multiplicative scale, suggesting that they synergistically influenced the development of pre-diabetes. Conclusions: The rural areas in Ningbo had a high prevalence of pre-diabetes. Overweight and obesity, hypertension, and elevated triglycerides were the major risk factors. There is a need of early intervention for preventing pre-diabetes. MDPI 2016-08-10 2016-08 /pmc/articles/PMC4997494/ /pubmed/27517947 http://dx.doi.org/10.3390/ijerph13080808 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhao, Ming
Lin, Hongbo
Yuan, Yanyan
Wang, Fuyan
Xi, Yang
Wen, Li Ming
Shen, Peng
Bu, Shizhong
Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China
title Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China
title_full Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China
title_fullStr Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China
title_full_unstemmed Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China
title_short Prevalence of Pre-Diabetes and Its Associated Risk Factors in Rural Areas of Ningbo, China
title_sort prevalence of pre-diabetes and its associated risk factors in rural areas of ningbo, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997494/
https://www.ncbi.nlm.nih.gov/pubmed/27517947
http://dx.doi.org/10.3390/ijerph13080808
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