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Hepatitis E Pathogenesis

Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients. This review describes how our understa...

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Detalles Bibliográficos
Autores principales: Lhomme, Sébastien, Marion, Olivier, Abravanel, Florence, Chapuy-Regaud, Sabine, Kamar, Nassim, Izopet, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997574/
https://www.ncbi.nlm.nih.gov/pubmed/27527210
http://dx.doi.org/10.3390/v8080212
Descripción
Sumario:Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients. This review describes how our understanding of the pathogenesis of HEV infection has progressed in recent years.