Loss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish

The Ewing sarcoma family of tumors expresses aberrant EWSR1- (EWS) fusion genes that are derived from chromosomal translocation. Although these fusion genes are well characterized as transcription factors, their formation leaves a single EWS allele in the sarcoma cells, and the contribution that the...

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Detalles Bibliográficos
Autores principales: Park, Hyewon, Galbraith, Richard, Turner, Thaddeus, Mehojah, Justin, Azuma, Mizuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997631/
https://www.ncbi.nlm.nih.gov/pubmed/27557633
http://dx.doi.org/10.1038/srep32297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997631/
https://www.ncbi.nlm.nih.gov/pubmed/27557633
http://dx.doi.org/10.1038/srep32297

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