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Auto-immune thyroid dysfunction induced by tyrosine kinase inhibitors in a patient with recurrent chordoma

BACKGROUND: While hypothyroidism has frequently been reported with the use of TKIs, the thyroid-stimulating hormone (TSH) suppressing effect of TKIs is rare, except for thyroiditis. We describe a case with progressive recurrent chordoma who initially became hyperthyroid in a context of autoimmunity...

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Detalles Bibliográficos
Autores principales: Eroukhmanoff, Juliette, Castinetti, Frederic, Penel, Nicolas, Salas, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997685/
https://www.ncbi.nlm.nih.gov/pubmed/27558389
http://dx.doi.org/10.1186/s12885-016-2705-3