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Intention-to-treat and transparency of related practices in randomized, controlled trials of anti-infectives

BACKGROUND: Intention-to-treat (ITT) analysis is commonly recommended for use, due to its benefits on external validity, in randomized, controlled trials (RCTs). No published reports describe how ITT analysis, as well as alternative approaches, are used in anti-infective RCTs. The purpose of this st...

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Detalles Bibliográficos
Autores principales: Beckett, Robert D., Loeser, Kathryn C., Bowman, Kathryn R., Towne, Trent G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997732/
https://www.ncbi.nlm.nih.gov/pubmed/27557676
http://dx.doi.org/10.1186/s12874-016-0215-2