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Abnormal plasma DNA profiles in early ovarian cancer using a non-invasive prenatal testing platform: implications for cancer screening

BACKGROUND: Non-invasive prenatal testing (NIPT) identifies fetal aneuploidy by sequencing cell-free DNA in the maternal plasma. Pre-symptomatic maternal malignancies have been incidentally detected during NIPT based on abnormal genomic profiles. This low coverage sequencing approach could have pote...

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Detalles Bibliográficos
Autores principales:	Cohen, Paul A., Flowers, Nicola, Tong, Stephen, Hannan, Natalie, Pertile, Mark D., Hui, Lisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997750/ https://www.ncbi.nlm.nih.gov/pubmed/27558279 http://dx.doi.org/10.1186/s12916-016-0667-6

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