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Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893

Staphylococcus aureus infections lead to an array of illnesses ranging from mild skin infections to serious diseases, such endocarditis, osteomyelitis, and pneumonia. Alpha-toxin (Hla) is a pore-forming toxin, encoded by the hla gene, that is thought to play a key role in S. aureus pathogenesis. A m...

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Detalles Bibliográficos
Autores principales:	Tabor, David E., Yu, Li, Mok, Hoyin, Tkaczyk, Christine, Sellman, Bret R., Wu, Yuling, Oganesyan, Vaheh, Slidel, Tim, Jafri, Hasan, McCarthy, Michael, Bradford, Patricia, Esser, Mark T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Epidemiology and Surveillance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997823/ https://www.ncbi.nlm.nih.gov/pubmed/27324766 http://dx.doi.org/10.1128/AAC.00357-16

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