Cargando…
A “Double-Edged” Scaffold: Antitumor Power within the Antibacterial Quinolone
In the late 1980s, reports emerged describing experimental antibacterial quinolones having significant potency against eukaryotic Type II topoisomerases (topo II) and showing cytotoxic activity against tumor cell lines. As a result, several pharmaceutical companies initiated quinolone anticancer pro...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bentham Science Publishers
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997924/ https://www.ncbi.nlm.nih.gov/pubmed/26695512 http://dx.doi.org/10.2174/0929867323666151223095839 |