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A “Double-Edged” Scaffold: Antitumor Power within the  Antibacterial Quinolone

In the late 1980s, reports emerged describing experimental antibacterial quinolones having significant potency against eukaryotic Type II topoisomerases (topo II) and showing cytotoxic activity against tumor cell lines. As a result, several pharmaceutical companies initiated quinolone anticancer pro...

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Detalles Bibliográficos
Autores principales:	Bisacchi, Gregory S., Hale, Michael R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997924/ https://www.ncbi.nlm.nih.gov/pubmed/26695512 http://dx.doi.org/10.2174/0929867323666151223095839

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