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Changes in Myocardial Composition and Conduction Properties in Rat Heart Failure Model Induced by Chronic Volume Overload

Volume overload leads to development of eccentric cardiac hypertrophy and heart failure. In our previous report, we have shown myocyte hypertrophy with no fibrosis and decrease in gap junctional coupling via connexin43 in a rat model of aorto-caval fistula at 21 weeks. Here we set to analyze the ele...

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Detalles Bibliográficos
Autores principales: Sedmera, David, Neckar, Jan, Benes, Jiri, Pospisilova, Jana, Petrak, Jiri, Sedlacek, Kamil, Melenovsky, Vojtech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997968/
https://www.ncbi.nlm.nih.gov/pubmed/27610087
http://dx.doi.org/10.3389/fphys.2016.00367