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Image based detection and targeting of therapy resistance in pancreatic adenocarcinoma

Pancreatic intraepithelial neoplasia (PanIN) is a premalignant lesion that can progress to pancreatic ductal adenocarcinoma, a highly lethal malignancy marked by its late stage at clinical presentation and profound drug resistance(1). The genomic alterations that commonly occur in pancreatic cancer...

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Detalles Bibliográficos
Autores principales: Fox, Raymond G., Lytle, Nikki K., Jaquish, Dawn V., Park, Frederick D., Ito, Takahiro, Bajaj, Jeevisha, Koechlein, Claire S., Zimdahl, Bryan, Yano, Masato, Kopp, Janel, Kritzik, Marcie, Sicklick, Jason, Sander, Maike, Grandgenett, Paul M., Hollingsworth, Michael A., Shibata, Shinsuke, Pizzo, Donald, Valasek, Mark, Sasik, Roman, Scadeng, Miriam, Okano, Hideyuki, Kim, Youngsoo, MacLeod, A. Robert, Lowy, Andrew M., Reya, Tannishtha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998062/
https://www.ncbi.nlm.nih.gov/pubmed/27281208
http://dx.doi.org/10.1038/nature17988