Cargando…
Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients
Neurological complications can occur in up to 51% of vertebral osteomyelitis (VO) in surgical series. The aim of our study was to estimate the frequency of neurological signs in a nonselected population of patients with VO and to assess clinical and MRI changes associated with these complications. W...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998243/ https://www.ncbi.nlm.nih.gov/pubmed/26817869 http://dx.doi.org/10.1097/MD.0000000000002373 |
_version_ | 1782449899736924160 |
---|---|
author | Bart, Géraldine Redon, Hervé Boutoille, David Hamel, Olivier Planche, Lucie Maugars, Yves Le Goff, Benoit |
author_facet | Bart, Géraldine Redon, Hervé Boutoille, David Hamel, Olivier Planche, Lucie Maugars, Yves Le Goff, Benoit |
author_sort | Bart, Géraldine |
collection | PubMed |
description | Neurological complications can occur in up to 51% of vertebral osteomyelitis (VO) in surgical series. The aim of our study was to estimate the frequency of neurological signs in a nonselected population of patients with VO and to assess clinical and MRI changes associated with these complications. We reviewed medical charts of patients with VO from 2007 to 2014 in our University Hospital and their MRIs were analyzed by a radiologist blinded from clinical data. Neurological status was defined as follow: normal, minor signs (radiculalgia or sensory loss), and major signs (motor deficit and/or sphincter dysfunction). A total of 121 patients were included. Mean age was 64.3 years. Overall, 50 patients (40%) had neurological signs, 26 were major signs (21.5%). Neurological signs were present at the time of admission in 37 patients and happened secondarily in 13 cases. MRI changes associated with major neurological signs were: Cervical involvement (P = 0.011), dural sac compression (P = 0.0012), ventral effacement of the subarachnoidal space (P < 0.001), compressive myelopathy (P = 0.006). More than 50% of the vertebral body destruction (P = 0.017), angular kyphosis (P = 0.016) partial or complete destruction of posterior arch (P = 0.032) were also associated with these signs. Neither epidural abscesses, multifocal lesions, loss of disk height, nor nerve roots compression were associated with major neurological signs. Neurological signs occurred in 40% of our patients with one half being major signs. Cervical involvement, vertebral destruction, angular kyphosis, dural compression, effacement of subarachnoid space and compressive myelopathy on MRI were risk factors associated with neurological complications. |
format | Online Article Text |
id | pubmed-4998243 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-49982432016-09-02 Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients Bart, Géraldine Redon, Hervé Boutoille, David Hamel, Olivier Planche, Lucie Maugars, Yves Le Goff, Benoit Medicine (Baltimore) 4900 Neurological complications can occur in up to 51% of vertebral osteomyelitis (VO) in surgical series. The aim of our study was to estimate the frequency of neurological signs in a nonselected population of patients with VO and to assess clinical and MRI changes associated with these complications. We reviewed medical charts of patients with VO from 2007 to 2014 in our University Hospital and their MRIs were analyzed by a radiologist blinded from clinical data. Neurological status was defined as follow: normal, minor signs (radiculalgia or sensory loss), and major signs (motor deficit and/or sphincter dysfunction). A total of 121 patients were included. Mean age was 64.3 years. Overall, 50 patients (40%) had neurological signs, 26 were major signs (21.5%). Neurological signs were present at the time of admission in 37 patients and happened secondarily in 13 cases. MRI changes associated with major neurological signs were: Cervical involvement (P = 0.011), dural sac compression (P = 0.0012), ventral effacement of the subarachnoidal space (P < 0.001), compressive myelopathy (P = 0.006). More than 50% of the vertebral body destruction (P = 0.017), angular kyphosis (P = 0.016) partial or complete destruction of posterior arch (P = 0.032) were also associated with these signs. Neither epidural abscesses, multifocal lesions, loss of disk height, nor nerve roots compression were associated with major neurological signs. Neurological signs occurred in 40% of our patients with one half being major signs. Cervical involvement, vertebral destruction, angular kyphosis, dural compression, effacement of subarachnoid space and compressive myelopathy on MRI were risk factors associated with neurological complications. Wolters Kluwer Health 2016-01-22 /pmc/articles/PMC4998243/ /pubmed/26817869 http://dx.doi.org/10.1097/MD.0000000000002373 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 4900 Bart, Géraldine Redon, Hervé Boutoille, David Hamel, Olivier Planche, Lucie Maugars, Yves Le Goff, Benoit Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients |
title | Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients |
title_full | Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients |
title_fullStr | Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients |
title_full_unstemmed | Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients |
title_short | Is There an Association Between Magnetic Resonance Imaging and Neurological Signs in Patients With Vertebral Osteomyelitis?: A Retrospective Observational Study on 121 Patients |
title_sort | is there an association between magnetic resonance imaging and neurological signs in patients with vertebral osteomyelitis?: a retrospective observational study on 121 patients |
topic | 4900 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998243/ https://www.ncbi.nlm.nih.gov/pubmed/26817869 http://dx.doi.org/10.1097/MD.0000000000002373 |
work_keys_str_mv | AT bartgeraldine isthereanassociationbetweenmagneticresonanceimagingandneurologicalsignsinpatientswithvertebralosteomyelitisaretrospectiveobservationalstudyon121patients AT redonherve isthereanassociationbetweenmagneticresonanceimagingandneurologicalsignsinpatientswithvertebralosteomyelitisaretrospectiveobservationalstudyon121patients AT boutoilledavid isthereanassociationbetweenmagneticresonanceimagingandneurologicalsignsinpatientswithvertebralosteomyelitisaretrospectiveobservationalstudyon121patients AT hamelolivier isthereanassociationbetweenmagneticresonanceimagingandneurologicalsignsinpatientswithvertebralosteomyelitisaretrospectiveobservationalstudyon121patients AT planchelucie isthereanassociationbetweenmagneticresonanceimagingandneurologicalsignsinpatientswithvertebralosteomyelitisaretrospectiveobservationalstudyon121patients AT maugarsyves isthereanassociationbetweenmagneticresonanceimagingandneurologicalsignsinpatientswithvertebralosteomyelitisaretrospectiveobservationalstudyon121patients AT legoffbenoit isthereanassociationbetweenmagneticresonanceimagingandneurologicalsignsinpatientswithvertebralosteomyelitisaretrospectiveobservationalstudyon121patients |