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The new indication of TEVAR for uncomplicated type B aortic dissection

The classical therapeutic indication for type B aortic dissection is based on either medication or open surgery; medication therapy is recommended for relatively stable uncomplicated type B aortic dissection. With improvements in endovascular repair and the potential risk of disease progression, it...

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Autores principales: Song, Chao, Lu, Qingsheng, Zhou, Jian, Yu, Guanyu, Feng, Xiang, Zhao, Zhiqing, Bao, Junmin, Feng, Rui, Jing, Zaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998319/
https://www.ncbi.nlm.nih.gov/pubmed/27336881
http://dx.doi.org/10.1097/MD.0000000000003919
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author Song, Chao
Lu, Qingsheng
Zhou, Jian
Yu, Guanyu
Feng, Xiang
Zhao, Zhiqing
Bao, Junmin
Feng, Rui
Jing, Zaiping
author_facet Song, Chao
Lu, Qingsheng
Zhou, Jian
Yu, Guanyu
Feng, Xiang
Zhao, Zhiqing
Bao, Junmin
Feng, Rui
Jing, Zaiping
author_sort Song, Chao
collection PubMed
description The classical therapeutic indication for type B aortic dissection is based on either medication or open surgery; medication therapy is recommended for relatively stable uncomplicated type B aortic dissection. With improvements in endovascular repair and the potential risk of disease progression, it is now necessary to evaluate the requirement for revision of the therapeutic choice of uncomplicated type B aortic dissection based on morphological features and time window. Data from 252 patients diagnosed as uncomplicated type B aortic dissection from 1992 to 2015 were analyzed retrospectively. Among these cases, 117 patients received medication therapy and 135 patients underwent endovascular repair. The 60-month survival rate in the endovascular group was higher than that in the medication group (92.3% vs 67.6%). According to the morphological evaluation, visceral artery involvement and false/true lumen ratios over 0.7 were strong risk factors for medical treatment alone. Increased surgical time and blood loss were found in patients treated in the chronic phase, compared with those who underwent endovascular repair within 14 days of the onset of symptoms. With improvements in aortic remodeling techniques, endovascular repair has been shown to improve long-term survival rates of patients with uncomplicated aortic dissection. Considering the potential risk of death, we recommend that patients with visceral artery involvement and a false/true lumen ratio over 0.7 should receive endovascular repair aggressively. Furthermore, delayed endovascular repair in the chronic phase does not improve the long-term outcome of uncomplicated type B aortic dissection.
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spelling pubmed-49983192016-09-02 The new indication of TEVAR for uncomplicated type B aortic dissection Song, Chao Lu, Qingsheng Zhou, Jian Yu, Guanyu Feng, Xiang Zhao, Zhiqing Bao, Junmin Feng, Rui Jing, Zaiping Medicine (Baltimore) 3400 The classical therapeutic indication for type B aortic dissection is based on either medication or open surgery; medication therapy is recommended for relatively stable uncomplicated type B aortic dissection. With improvements in endovascular repair and the potential risk of disease progression, it is now necessary to evaluate the requirement for revision of the therapeutic choice of uncomplicated type B aortic dissection based on morphological features and time window. Data from 252 patients diagnosed as uncomplicated type B aortic dissection from 1992 to 2015 were analyzed retrospectively. Among these cases, 117 patients received medication therapy and 135 patients underwent endovascular repair. The 60-month survival rate in the endovascular group was higher than that in the medication group (92.3% vs 67.6%). According to the morphological evaluation, visceral artery involvement and false/true lumen ratios over 0.7 were strong risk factors for medical treatment alone. Increased surgical time and blood loss were found in patients treated in the chronic phase, compared with those who underwent endovascular repair within 14 days of the onset of symptoms. With improvements in aortic remodeling techniques, endovascular repair has been shown to improve long-term survival rates of patients with uncomplicated aortic dissection. Considering the potential risk of death, we recommend that patients with visceral artery involvement and a false/true lumen ratio over 0.7 should receive endovascular repair aggressively. Furthermore, delayed endovascular repair in the chronic phase does not improve the long-term outcome of uncomplicated type B aortic dissection. Wolters Kluwer Health 2016-06-24 /pmc/articles/PMC4998319/ /pubmed/27336881 http://dx.doi.org/10.1097/MD.0000000000003919 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-sa/4.0 This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0
spellingShingle 3400
Song, Chao
Lu, Qingsheng
Zhou, Jian
Yu, Guanyu
Feng, Xiang
Zhao, Zhiqing
Bao, Junmin
Feng, Rui
Jing, Zaiping
The new indication of TEVAR for uncomplicated type B aortic dissection
title The new indication of TEVAR for uncomplicated type B aortic dissection
title_full The new indication of TEVAR for uncomplicated type B aortic dissection
title_fullStr The new indication of TEVAR for uncomplicated type B aortic dissection
title_full_unstemmed The new indication of TEVAR for uncomplicated type B aortic dissection
title_short The new indication of TEVAR for uncomplicated type B aortic dissection
title_sort new indication of tevar for uncomplicated type b aortic dissection
topic 3400
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998319/
https://www.ncbi.nlm.nih.gov/pubmed/27336881
http://dx.doi.org/10.1097/MD.0000000000003919
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