Combination With Low-dose Dextromethorphan Improves the Effect of Amlodipine Monotherapy in Clinical Hypertension: A First-in-human, Concept-proven, Prospective, Dose-escalation, Multicenter Study

The combination of low rather than high dose of dextromethorphan (DXM) with amlodipine (AM) could improve blood pressure (BP) reduction in hypertensive animals. The study aimed to evaluate the feasibility of different doses of DXM combined with standard AM treatment in clinical hypertension. This wa...

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Detalles Bibliográficos
Autores principales: Yin, Wei-Hsian, Chen, Pei, Yeh, Hung-I, Wang, Kuo-Yang, Hung, Yi-Jen, Tseng, Wei-Kung, Wen, Ming-Shien, Wu, Tao-Cheng, Wu, Chau-Chung, Cheng, Shu-Meng, Chen, Jaw-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
3400
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998419/
https://www.ncbi.nlm.nih.gov/pubmed/27015224
http://dx.doi.org/10.1097/MD.0000000000003234

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