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Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature

The Charcot–Marie–Tooth disease (CMT) causes significant muscular deficits in the affected patients, restricts daily activities (ADL), and involves a severe disability. Although the conservative intervention is the only treatment for the disease, there is no scientific evidence so far on rehabilitat...

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Autores principales: Corrado, Bruno, Ciardi, Gianluca, Bargigli, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998680/
https://www.ncbi.nlm.nih.gov/pubmed/27124017
http://dx.doi.org/10.1097/MD.0000000000003278
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author Corrado, Bruno
Ciardi, Gianluca
Bargigli, Chiara
author_facet Corrado, Bruno
Ciardi, Gianluca
Bargigli, Chiara
author_sort Corrado, Bruno
collection PubMed
description The Charcot–Marie–Tooth disease (CMT) causes significant muscular deficits in the affected patients, restricts daily activities (ADL), and involves a severe disability. Although the conservative intervention is the only treatment for the disease, there is no scientific evidence so far on rehabilitation treatment. Objectives of the review are: research the best literary evidence so far on the rehabilitation treatment of CMT; critically analyze the outcome, to build an evidence-based work protocol. A systematic review of the rehabilitation of a patient with CMT, including the results from the following databases: Pubmed, Medline, Embase, Pedro, Cinahl, Ebsco discovery. Criteria for inclusion: randomized/controlled studies, analytic studies, transversal studies on a cohort of at least 10 individuals; medium/long-term report of the results. Eleven studies in total have been admitted to the final review phase; trials about physiotherapy CMT treatment (5), about orthosis treatment (6). Despite the wide range of outcomes and proposed interventions, the data points to the following: strength or endurance trainings improve functionality and ADLs of affected patients, while orthotic role is, at the moment, not completely clear. Physiotherapy treatment is a useful tool to manage CMT; more studies on a larger number of cases are needed to define orthosis utility and to establish the gold standard of the treatment.
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spelling pubmed-49986802016-09-06 Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature Corrado, Bruno Ciardi, Gianluca Bargigli, Chiara Medicine (Baltimore) 6300 The Charcot–Marie–Tooth disease (CMT) causes significant muscular deficits in the affected patients, restricts daily activities (ADL), and involves a severe disability. Although the conservative intervention is the only treatment for the disease, there is no scientific evidence so far on rehabilitation treatment. Objectives of the review are: research the best literary evidence so far on the rehabilitation treatment of CMT; critically analyze the outcome, to build an evidence-based work protocol. A systematic review of the rehabilitation of a patient with CMT, including the results from the following databases: Pubmed, Medline, Embase, Pedro, Cinahl, Ebsco discovery. Criteria for inclusion: randomized/controlled studies, analytic studies, transversal studies on a cohort of at least 10 individuals; medium/long-term report of the results. Eleven studies in total have been admitted to the final review phase; trials about physiotherapy CMT treatment (5), about orthosis treatment (6). Despite the wide range of outcomes and proposed interventions, the data points to the following: strength or endurance trainings improve functionality and ADLs of affected patients, while orthotic role is, at the moment, not completely clear. Physiotherapy treatment is a useful tool to manage CMT; more studies on a larger number of cases are needed to define orthosis utility and to establish the gold standard of the treatment. Wolters Kluwer Health 2016-04-29 /pmc/articles/PMC4998680/ /pubmed/27124017 http://dx.doi.org/10.1097/MD.0000000000003278 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 6300
Corrado, Bruno
Ciardi, Gianluca
Bargigli, Chiara
Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature
title Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature
title_full Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature
title_fullStr Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature
title_full_unstemmed Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature
title_short Rehabilitation Management of the Charcot–Marie–Tooth Syndrome: A Systematic Review of the Literature
title_sort rehabilitation management of the charcot–marie–tooth syndrome: a systematic review of the literature
topic 6300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998680/
https://www.ncbi.nlm.nih.gov/pubmed/27124017
http://dx.doi.org/10.1097/MD.0000000000003278
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