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Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study

In previous studies of transverse sinus (TS) hypoplasia, discrepancies between TS diameter measured by magnetic resonance venography (MRV) and contrast T1-weighted magnetic resonance (contrast T1) were observed. To investigate these discrepancies, and considering that TS hypoplasia is associated wit...

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Autores principales: Han, Ke, Chao, A-Ching, Chang, Feng-Chi, Hsu, Hung-Yi, Chung, Chih-Ping, Sheng, Wen-Yung, Chan, Lung, Wu, Jiang, Hu, Han-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998862/
https://www.ncbi.nlm.nih.gov/pubmed/26962781
http://dx.doi.org/10.1097/MD.0000000000002862
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author Han, Ke
Chao, A-Ching
Chang, Feng-Chi
Hsu, Hung-Yi
Chung, Chih-Ping
Sheng, Wen-Yung
Chan, Lung
Wu, Jiang
Hu, Han-Hwa
author_facet Han, Ke
Chao, A-Ching
Chang, Feng-Chi
Hsu, Hung-Yi
Chung, Chih-Ping
Sheng, Wen-Yung
Chan, Lung
Wu, Jiang
Hu, Han-Hwa
author_sort Han, Ke
collection PubMed
description In previous studies of transverse sinus (TS) hypoplasia, discrepancies between TS diameter measured by magnetic resonance venography (MRV) and contrast T1-weighted magnetic resonance (contrast T1) were observed. To investigate these discrepancies, and considering that TS hypoplasia is associated with neurological disorders, we performed a post hoc analysis of prospectively collected data from 3 case–control studies on transient global amnesia (TGA), transient monocular blindness (TMB), and panic disorders while retaining the original inclusion and exclusion criteria. Magnetic resonance (MR) imaging of 131 subjects was reviewed to evaluate TS diameter and the location and degree of venous flow stenosis and obstruction. MRV without contrast revealed that TS hypoplasia was observed in 69 subjects, whom we classified into 2 subgroups according to the concordance with contrast T1 observations: concordance indicated anatomically small TS (30 subjects), and discrepancy indicated that the MRV diagnosis is in fact flow-related and that TS is not anatomically small (39 subjects). The latter subgroup was associated with at least 1 site of venous compression/stenosis in the internal jugular vein (IJV) or the left brachiocephalic vein (BCV) (P < 0.001), which was significantly larger in patients than controls. Compensatory dilatation of contralateral TS diameter was only observed with MRV, not with contrast T1 imaging. The clinical implication of these results is that using MRV only, IJV/BCV compression/stenosis may be misdiagnosed as TS hypoplasia. And contralateral TS have no compensatory dilatation in its diameter in contrast T1 imaging, just compensatory increased flow volume.
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spelling pubmed-49988622016-08-29 Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study Han, Ke Chao, A-Ching Chang, Feng-Chi Hsu, Hung-Yi Chung, Chih-Ping Sheng, Wen-Yung Chan, Lung Wu, Jiang Hu, Han-Hwa Medicine (Baltimore) 5300 In previous studies of transverse sinus (TS) hypoplasia, discrepancies between TS diameter measured by magnetic resonance venography (MRV) and contrast T1-weighted magnetic resonance (contrast T1) were observed. To investigate these discrepancies, and considering that TS hypoplasia is associated with neurological disorders, we performed a post hoc analysis of prospectively collected data from 3 case–control studies on transient global amnesia (TGA), transient monocular blindness (TMB), and panic disorders while retaining the original inclusion and exclusion criteria. Magnetic resonance (MR) imaging of 131 subjects was reviewed to evaluate TS diameter and the location and degree of venous flow stenosis and obstruction. MRV without contrast revealed that TS hypoplasia was observed in 69 subjects, whom we classified into 2 subgroups according to the concordance with contrast T1 observations: concordance indicated anatomically small TS (30 subjects), and discrepancy indicated that the MRV diagnosis is in fact flow-related and that TS is not anatomically small (39 subjects). The latter subgroup was associated with at least 1 site of venous compression/stenosis in the internal jugular vein (IJV) or the left brachiocephalic vein (BCV) (P < 0.001), which was significantly larger in patients than controls. Compensatory dilatation of contralateral TS diameter was only observed with MRV, not with contrast T1 imaging. The clinical implication of these results is that using MRV only, IJV/BCV compression/stenosis may be misdiagnosed as TS hypoplasia. And contralateral TS have no compensatory dilatation in its diameter in contrast T1 imaging, just compensatory increased flow volume. Wolters Kluwer Health 2016-03-11 /pmc/articles/PMC4998862/ /pubmed/26962781 http://dx.doi.org/10.1097/MD.0000000000002862 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 5300
Han, Ke
Chao, A-Ching
Chang, Feng-Chi
Hsu, Hung-Yi
Chung, Chih-Ping
Sheng, Wen-Yung
Chan, Lung
Wu, Jiang
Hu, Han-Hwa
Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study
title Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study
title_full Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study
title_fullStr Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study
title_full_unstemmed Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study
title_short Diagnosis of Transverse Sinus Hypoplasia in Magnetic Resonance Venography: New Insights Based on Magnetic Resonance Imaging in Combined Dataset of Venous Outflow Impairment Case–Control Studies: Post Hoc Case–Control Study
title_sort diagnosis of transverse sinus hypoplasia in magnetic resonance venography: new insights based on magnetic resonance imaging in combined dataset of venous outflow impairment case–control studies: post hoc case–control study
topic 5300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998862/
https://www.ncbi.nlm.nih.gov/pubmed/26962781
http://dx.doi.org/10.1097/MD.0000000000002862
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