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Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation
In a treatment planning study, radiosurgical treatment plans designed to produce lesions on the left atrium were created using two different methodologies. In one, structures in the heart (mitral valve and coronary arteries) were designated as critical structures while this was not done in the secon...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999153/ https://www.ncbi.nlm.nih.gov/pubmed/27610282 http://dx.doi.org/10.7759/cureus.703 |
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author | Gardner, Edward A Weidlich, Georg A. |
author_facet | Gardner, Edward A Weidlich, Georg A. |
author_sort | Gardner, Edward A |
collection | PubMed |
description | In a treatment planning study, radiosurgical treatment plans designed to produce lesions on the left atrium were created using two different methodologies. In one, structures in the heart (mitral valve and coronary arteries) were designated as critical structures while this was not done in the second plan. The treatment plans that were created were compared with standards for heart dose used when treating spine tumors. Although the dosage for the whole heart greatly exceeded the dose standards, when only the dose to the ventricles was considered, the plan where the mitral valve was spared was very close to the dose standards. The ventricles received a substantially higher dose in the plan where the mitral valve was not a critical structure. Although neither treatment plan was delivered, this study demonstrated the feasibility of treating the heart while minimizing dose to the ventricles. |
format | Online Article Text |
id | pubmed-4999153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-49991532016-09-08 Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation Gardner, Edward A Weidlich, Georg A. Cureus Radiation Oncology In a treatment planning study, radiosurgical treatment plans designed to produce lesions on the left atrium were created using two different methodologies. In one, structures in the heart (mitral valve and coronary arteries) were designated as critical structures while this was not done in the second plan. The treatment plans that were created were compared with standards for heart dose used when treating spine tumors. Although the dosage for the whole heart greatly exceeded the dose standards, when only the dose to the ventricles was considered, the plan where the mitral valve was spared was very close to the dose standards. The ventricles received a substantially higher dose in the plan where the mitral valve was not a critical structure. Although neither treatment plan was delivered, this study demonstrated the feasibility of treating the heart while minimizing dose to the ventricles. Cureus 2016-07-18 /pmc/articles/PMC4999153/ /pubmed/27610282 http://dx.doi.org/10.7759/cureus.703 Text en Copyright © 2016, Gardner et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Radiation Oncology Gardner, Edward A Weidlich, Georg A. Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation |
title | Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation |
title_full | Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation |
title_fullStr | Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation |
title_full_unstemmed | Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation |
title_short | Analysis of Dose Distribution in the Heart for Radiosurgical Ablation of Atrial Fibrillation |
title_sort | analysis of dose distribution in the heart for radiosurgical ablation of atrial fibrillation |
topic | Radiation Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999153/ https://www.ncbi.nlm.nih.gov/pubmed/27610282 http://dx.doi.org/10.7759/cureus.703 |
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