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Non-Familial Cherubism with Bilateral Maxilla and Mandible Involvement – Clinicoradiographic Findings

Cherubism is a self-limiting non-neoplastic autosomal dominant fibro-osseous syndrome of the jaws. It is occasionally manifested before the age of two years. It occurs in children and more often in boys. It is characterized by notable clinical bilateral swelling of the cheeks due to a bony enlargeme...

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Detalles Bibliográficos
Autores principales: Ali, Ibrahim K, Karjodkar, Freny R, Sansare, Kaustubh, Salve, Prashant, Dora, Amaresh C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999156/
https://www.ncbi.nlm.nih.gov/pubmed/27588230
http://dx.doi.org/10.7759/cureus.709
Descripción
Sumario:Cherubism is a self-limiting non-neoplastic autosomal dominant fibro-osseous syndrome of the jaws. It is occasionally manifested before the age of two years. It occurs in children and more often in boys. It is characterized by notable clinical bilateral swelling of the cheeks due to a bony enlargement of the jaws that impart a characteristic ‘cherubic’ look. Regression occurs in the course of puberty leaving a few facial deformities and malocclusion. Cherubism might occur in solitary cases or in several members of the family, often in many generations. The reported case is an example of solitary sporadic occurrence within a family, which is a rarely documented condition in the literature.