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Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes

Codon usage bias affects protein translation because tRNAs that recognize synonymous codons differ in their abundance. Although the current dogma states that tRNA expression is exclusively regulated by intrinsic control elements (A- and B-box sequences), we revealed, using a reporter that monitors t...

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Detalles Bibliográficos
Autores principales: Sagi, Dror, Rak, Roni, Gingold, Hila, Adir, Idan, Maayan, Gadi, Dahan, Orna, Broday, Limor, Pilpel, Yitzhak, Rechavi, Oded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999229/
https://www.ncbi.nlm.nih.gov/pubmed/27560950
http://dx.doi.org/10.1371/journal.pgen.1006264