Cargando…

Prothrombin Kringle-2: A Potential Inflammatory Pathogen in the Parkinsonian Dopaminergic System

Although accumulating evidence suggests that microglia-mediated neuroinflammation may be crucial for the initiation and progression of Parkinson's disease (PD), and that the control of neuroinflammation may be a useful strategy for preventing the degeneration of nigrostriatal dopaminergic (DA)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leem, Eunju, Jeong, Kyoung Hoon, Won, So-Yoon, Shin, Won-Ho, Kim, Sang Ryong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Brain and Neural Science 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999420/ https://www.ncbi.nlm.nih.gov/pubmed/27574481 http://dx.doi.org/10.5607/en.2016.25.4.147

Ejemplares similares

Induction of microglial toll-like receptor 4 by prothrombin kringle-2: a potential pathogenic mechanism in Parkinson’s disease
por: Shin, Won-Ho, et al.
Publicado: (2015)

Control of hippocampal prothrombin kringle‐2 (pKr‐2) expression reduces neurotoxic symptoms in five familial Alzheimer's disease mice
por: Kim, Sehwan, et al.
Publicado: (2021)

Prothrombin kringle-2, a mediator of microglial activation: new insight in Alzheimer’s disease pathogenesis
por: Lee, Jae Man, et al.
Publicado: (2022)

Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish
por: Grzegorski, Steven J., et al.
Publicado: (2020)

Naringin: A Protector of the Nigrostriatal Dopaminergic Projection
por: Jung, Un Ju, et al.
Publicado: (2014)

Interleukin-13 Propagates Prothrombin Kringle-2-Induced Neurotoxicity in Hippocampi In Vivo via Oxidative Stress
por: Jeong, Jae Yeong, et al.
Publicado: (2021)

Interleukin-4 and Interleukin-13 Exacerbate Neurotoxicity of Prothrombin Kringle-2 in Cortex In Vivo via Oxidative Stress
por: Jeong, Jae Yeong, et al.
Publicado: (2019)

Interleukin-4-Mediated Oxidative Stress Is Harmful to Hippocampal Neurons of Prothrombin Kringle-2-Lesioned Rat In Vivo
por: Chung, Young Cheul, et al.
Publicado: (2020)

Miguel Llinás and the Structure of the Kringle Fold
por: Patthy, Laszlo
Publicado: (2021)

Limited therapeutic potential of astrocyte elevated gene-1 transduction in an animal model of Parkinson's disease
por: Leem, Eunju, et al.
Publicado: (2020)

Simvastatin Prevents Dopaminergic Neurodegeneration in Experimental Parkinsonian Models: The Association with Anti-Inflammatory Responses
por: Yan, Junqiang, et al.
Publicado: (2011)

NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian Mice
por: Hernandes, Marina S., et al.
Publicado: (2013)

Conditioned Medium Protects Dopaminergic Neurons in Parkinsonian Rats
por: Nakhaeifard, Malihe, et al.
Publicado: (2018)

Different Dopaminergic Dysfunctions Underlying Parkinsonian Akinesia and Tremor
por: Caligiore, Daniele, et al.
Publicado: (2019)

The Parkinsonian mimetic, 6-OHDA, impairs axonal transport in dopaminergic axons
por: Lu, Xi, et al.
Publicado: (2014)

CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes
por: Zhang, Wenlong, et al.
Publicado: (2020)

Role of the kringle‐like domain in glycoprotein NMB for its tumorigenic potential
por: Xie, Rudy, et al.
Publicado: (2019)

Activation of CNTF/CNTFRα Signaling Pathway by hRheb(S16H) Transduction of Dopaminergic Neurons In Vivo
por: Jeong, Kyoung Hoon, et al.
Publicado: (2015)

Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian rats
por: Taravini, Irene RE, et al.
Publicado: (2011)

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss
por: Tain, Luke S, et al.
Publicado: (2009)

Dopaminergic Modulation of Spectral and Spatial Characteristics of Parkinsonian Subthalamic Nucleus Beta Bursts
por: Sure, Matthias, et al.
Publicado: (2021)

Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo
por: Leem, Eunju, et al.
Publicado: (2018)

DDC-Promoter-Driven Chemogenetic Activation of SNpc Dopaminergic Neurons Alleviates Parkinsonian Motor Symptoms
por: Seo, Dong-Chan, et al.
Publicado: (2023)

Antiangiogenic Therapy with Human Apolipoprotein(a) Kringle V and Paclitaxel in a Human Ovarian Cancer Mouse Model()()
por: Yu, Hyun-Kyung, et al.
Publicado: (2014)

Potential Role of Kringle-Integrin Interaction in Plasmin and uPA Actions (A Hypothesis)
por: Takada, Yoshikazu
Publicado: (2012)

22(R)-hydroxycholesterol for dopaminergic neuronal specification of MSCs and amelioration of Parkinsonian symptoms in rats
por: Singh, Manisha, et al.
Publicado: (2021)

Suppression of Colorectal Cancer Liver Metastasis by Apolipoprotein(a) Kringle V in a Nude Mouse Model through the Induction of Apoptosis in Tumor-Associated Endothelial Cells
por: Ahn, Jin-Hyung, et al.
Publicado: (2014)

Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice
por: Sgobio, Carmelo, et al.
Publicado: (2019)

Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes
por: Yang, Hao, et al.
Publicado: (2019)

The Treadmill Exercise Protects against Dopaminergic Neuron Loss and Brain Oxidative Stress in Parkinsonian Rats
por: da Costa, Roberta Oliveira, et al.
Publicado: (2017)

EANM practice guideline/SNMMI procedure standard for dopaminergic imaging in Parkinsonian syndromes 1.0
por: Morbelli, Silvia, et al.
Publicado: (2020)

Human Apolipoprotein(a) Kringle V Inhibits Ischemia-Induced Retinal Neovascularization via Suppression of Fibronectin-Mediated Angiogenesis
por: Lim, Yangmi, et al.
Publicado: (2012)

Corrigendum to “The Treadmill Exercise Protects against Dopaminergic Neuron Loss and Brain Oxidative Stress in Parkinsonian Rats”
por: da Costa, Roberta Oliveira, et al.
Publicado: (2018)

Tetranectin Binds to the Kringle 1-4 Form of Angiostatin and Modifies Its Functional Activity
por: Mogues, Tirsit, et al.
Publicado: (2004)

Voltage-Dependent Anion Channel-1, a Possible Ligand of Plasminogen Kringle 5
por: Liang, Yin-ku, et al.
Publicado: (2016)

Control of Reactive Oxygen Species for the Prevention of Parkinson’s Disease: The Possible Application of Flavonoids
por: Kim, Tae Yeon, et al.
Publicado: (2020)

Ectopic Pregnancy-Derived Human Trophoblastic Stem Cells Regenerate Dopaminergic Nigrostriatal Pathway to Treat Parkinsonian Rats
por: Lee, Tony Tung-Yin, et al.
Publicado: (2012)

Azilsartan ameliorates apoptosis of dopaminergic neurons and rescues characteristic parkinsonian behaviors in a rat model of Parkinson’s disease
por: Gao, Qing, et al.
Publicado: (2017)

GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and Tideglusib
por: Li, Junyu, et al.
Publicado: (2020)

Parkinsonian phenotypes induced by Synphilin-1 expression are differentially contributed by serotonergic and dopaminergic circuits and suppressed by nicotine treatment
por: Carvajal-Oliveros, Angel, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hnk1pdshd5a1atmij5l6qso26t