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Comparison of in vitro antileukemic activity of obatoclax and ABT-737
Obatoclax and ABT-737 belong to a new class of anticancer agents known as BH3-mimetics. These agents antagonize the anti-apoptotic members of Bcl-2 family. The Bcl-2 proteins modulate sensitivity of many types of cancer cells to chemotherapy. Therefore, the objective of the present study was to exam...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999481/ https://www.ncbi.nlm.nih.gov/pubmed/26880588 http://dx.doi.org/10.1007/s13277-016-4943-z |