Graft-infiltrating host dendritic cells play a key role in organ transplant rejection

Successful engraftment of organ transplants has traditionally relied on preventing the activation of recipient (host) T cells. Once T-cell activation has occurred, however, stalling the rejection process becomes increasingly difficult, leading to graft failure. Here we demonstrate that graft-infiltr...

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Detalles Bibliográficos
Autores principales: Zhuang, Quan, Liu, Quan, Divito, Sherrie J., Zeng, Qiang, Yatim, Karim M., Hughes, Andrew D., Rojas-Canales, Darling M., Nakao, A., Shufesky, William J., Williams, Amanda L., Humar, Rishab, Hoffman, Rosemary A., Shlomchik, Warren D., Oberbarnscheidt, Martin H., Lakkis, Fadi G., Morelli, Adrian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999515/
https://www.ncbi.nlm.nih.gov/pubmed/27554168
http://dx.doi.org/10.1038/ncomms12623

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