Cargando…

A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development

An arthropod-borne virus, Zika virus (ZIKV), has recently emerged as a major human pathogen. Associated with complications during perinatal development and Guillain-Barré syndrome in adults, ZIKV raises new challenges for understanding the molecular determinants of flavivirus pathogenesis. This unde...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsetsarkin, Konstantin A., Kenney, Heather, Chen, Rubing, Liu, Guangping, Manukyan, Hasmik, Whitehead, Stephen S., Laassri, Majid, Chumakov, Konstantin, Pletnev, Alexander G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999549/ https://www.ncbi.nlm.nih.gov/pubmed/27555311 http://dx.doi.org/10.1128/mBio.01114-16

Ejemplares similares

Epididymal epithelium propels early sexual transmission of Zika virus in the absence of interferon signaling
por: Pletnev, Alexander G., et al.
Publicado: (2021)

Multiplex PCR-Based Neutralization (MPBN) Assay for Titers Determination of the Three Types of Anti-Poliovirus Neutralizing-Antibodies
por: Manukyan, Hasmik, et al.
Publicado: (2020)

Development of a Quantitative One-Step RT-PCR Method for the Detection of Sabin 2 Virus Contamination in a Novel Oral Poliovirus Vaccine Type 2
por: Manukyan, Hasmik, et al.
Publicado: (2021)

Zika virus tropism during early infection of the testicular interstitium and its role in viral pathogenesis in the testes
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2020)

Multiplex PCR-based titration (MPBT) assay for determination of infectious titers of the three Sabin strains of live poliovirus vaccine
por: Manukyan, Hasmik, et al.
Publicado: (2019)

Improvement of the qmosRT-PCR Assay and Its Application for the Detection and Quantitation of the Three Serotypes of the Novel Oral Polio Vaccine in Stool Samples
por: Manukyan, Hasmik, et al.
Publicado: (2023)

Routes of Zika virus dissemination in the testis and epididymis of immunodeficient mice
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2018)

The Roles of prM-E Proteins in Historical and Epidemic Zika Virus-mediated Infection and Neurocytotoxicity
por: Li, Ge, et al.
Publicado: (2019)

Kissing-loop interaction between 5′ and 3′ ends of tick-borne Langat virus genome ‘bridges the gap’ between mosquito- and tick-borne flaviviruses in mechanisms of viral RNA cyclization: applications for virus attenuation and vaccine development
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2016)

Quantitative RT-PCR Assays for Quantification of Undesirable Mutants in the Novel Type 2 Oral Poliovirus Vaccine
por: Manukyan, Hasmik, et al.
Publicado: (2022)

Insights from the comparison of genomic variants from two influenza B viruses grown in the presence of human antibodies in cell culture
por: Plant, Ewan P., et al.
Publicado: (2020)

Stable and Highly Immunogenic MicroRNA-Targeted Single-Dose Live Attenuated Vaccine Candidate against Tick-Borne Encephalitis Constructed Using Genetic Backbone of Langat Virus
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2019)

Dual miRNA Targeting Restricts Host Range and Attenuates Neurovirulence of Flaviviruses
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2015)

Concurrent micro-RNA mediated silencing of tick-borne flavivirus replication in tick vector and in the brain of vertebrate host
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2016)

Novel Approach for Insertion of Heterologous Sequences into Full-Length ZIKV Genome Results in Superior Level of Gene Expression and Insert Stability
por: Volkova, Evgeniya, et al.
Publicado: (2020)

The preparation of an infectious full-length cDNA clone of Saffold virus
por: Himeda, Toshiki, et al.
Publicado: (2011)

Synergistic Internal Ribosome Entry Site/MicroRNA-Based Approach for Flavivirus Attenuation and Live Vaccine Development
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2017)

Tet-Inducible Production of Infectious Zika Virus from the Full-Length cDNA Clones of African- and Asian-Lineage Strains
por: Zhang, Lizhou, et al.
Publicado: (2018)

Chikungunya Virus 3′ Untranslated Region: Adaptation to Mosquitoes and a Population Bottleneck as Major Evolutionary Forces
por: Chen, Rubing, et al.
Publicado: (2013)

Rescue of the 1947 Zika Virus Prototype Strain with a Cytomegalovirus Promoter-Driven cDNA Clone
por: Schwarz, Megan C., et al.
Publicado: (2016)

Development of the full-length cDNA clones of two porcine epidemic diarrhea disease virus isolates with different virulence
por: Li, Jie, et al.
Publicado: (2017)

Development of a Full-Length Infectious Cdna Clone of the Grapevine Berry Inner Necrosis Virus
por: Fan, Xudong, et al.
Publicado: (2020)

Immune Pressure on Polymorphous Influenza B Populations Results in Diverse Hemagglutinin Escape Mutants and Lineage Switching
por: Plant, Ewan P., et al.
Publicado: (2020)

In vivo rescue of recombinant Zika virus from an infectious cDNA clone and its implications in vaccine development
por: Ávila-Pérez, Gines, et al.
Publicado: (2020)

Deep Sequencing for Evaluation of Genetic Stability of Influenza A/California/07/2009 (H1N1) Vaccine Viruses
por: Majid, Laassri, et al.
Publicado: (2015)

Synthesis and Characterization of a Full-Length Infectious cDNA Clone of Tomato Mottle Mosaic Virus
por: Tu, Liqin, et al.
Publicado: (2021)

Sequential Adaptive Mutations Enhance Efficient Vector Switching by Chikungunya Virus and Its Epidemic Emergence
por: Tsetsarkin, Konstantin A., et al.
Publicado: (2011)

Detection and discrimination of orthopoxviruses using microarrays of immobilized oligonucleotides
por: Laassri, Majid, et al.
Publicado: (2003)

Rapid Construction of Stable Infectious Full-Length cDNA Clone of Papaya Leaf Distortion Mosaic Virus Using In-Fusion Cloning
por: Tuo, Decai, et al.
Publicado: (2015)

The full-ORF clone resource of the German cDNA Consortium
por: Bechtel, Stephanie, et al.
Publicado: (2007)

Strategy for efficient generation of numerous full-length cDNA clones of classical swine fever virus for haplotyping
por: Johnston, Camille Melissa, et al.
Publicado: (2018)

Characterization of a Pathogenic Full-Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A
por: Beall, Anne, et al.
Publicado: (2016)

Unusual, stable replicating viruses generated from mumps virus cDNA clones
por: Bamford, Connor, et al.
Publicado: (2019)

Characterization of a pathogenic full-length cDNA clone of a virulent porcine epidemic diarrhea virus strain AH2012/12 in China
por: Fan, Baochao, et al.
Publicado: (2017)

A Single Mutation in Chikungunya Virus Affects Vector Specificity and Epidemic Potential
por: Tsetsarkin, Konstantin A, et al.
Publicado: (2007)

A cDNA Clone-Launched Platform for High-Yield Production of Inactivated Zika Vaccine
por: Yang, Yujiao, et al.
Publicado: (2017)

Mapping the cryptic spread of the 2015–2016 global Zika virus epidemic
por: Sun, Haoyang, et al.
Publicado: (2020)

Evaluation and validation of next-generation sequencing to support lot release for a novel type 2 oral poliovirus vaccine
por: Konz, John O., et al.
Publicado: (2021)

Phylogeny of Zika Virus in Western Hemisphere, 2015
por: Lanciotti, Robert S., et al.
Publicado: (2016)

Zika Virus Outbreak, Barbados, 2015–2016
por: Ryan, Sadie J., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1b862jk2nitmohh9jcv5fq82ri