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α‐synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease
OBJECTIVE: Progressive accumulation of α‐synuclein (α‐syn) has been associated with Parkinson's disease (PD) and Dementia with Lewy body (DLB). The mechanisms through which α‐syn leads to neurodegeneration are not completely clear; however, the formation of various oligomeric species have been...
Autores principales: | Spencer, Brian, Williams, Stephanie, Rockenstein, Edward, Valera, Elvira, Xin, Wei, Mante, Michael, Florio, Jazmin, Adame, Anthony, Masliah, Eliezer, Sierks, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999592/ https://www.ncbi.nlm.nih.gov/pubmed/27606342 http://dx.doi.org/10.1002/acn3.321 |
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