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Model‐Based Assessment of Alternative Study Designs in Pediatric Trials. Part II: Bayesian Approaches

This study presents a pharmacokinetic‐pharmacodynamic based clinical trial simulation framework for evaluating the performance of a fixed‐sample Bayesian design (BD) and two alternative Bayesian sequential designs (BSDs) (i.e., a non‐hierarchical (NON‐H) and a semi‐hierarchical (SEMI‐H) one). Prior...

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Detalles Bibliográficos
Autores principales: Smania, G, Baiardi, P, Ceci, A, Cella, M, Magni, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999603/
https://www.ncbi.nlm.nih.gov/pubmed/27530374
http://dx.doi.org/10.1002/psp4.12092

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