AMPK-independent inhibition of human macrophage ER stress response by AICAR

Obesity-associated insulin resistance is driven by inflammatory processes in response to metabolic overload. Obesity-associated inflammation can be recapitulated in cell culture by exposing macrophages to saturated fatty acids (SFA), and endoplasmic reticulum (ER) stress responses essentially contri...

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Detalles Bibliográficos
Autores principales: Boß, Marcel, Newbatt, Yvette, Gupta, Sahil, Collins, Ian, Brüne, Bernhard, Namgaladze, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999824/
https://www.ncbi.nlm.nih.gov/pubmed/27562249
http://dx.doi.org/10.1038/srep32111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999824/
https://www.ncbi.nlm.nih.gov/pubmed/27562249
http://dx.doi.org/10.1038/srep32111

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