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AMPK-independent inhibition of human macrophage ER stress response by AICAR

Obesity-associated insulin resistance is driven by inflammatory processes in response to metabolic overload. Obesity-associated inflammation can be recapitulated in cell culture by exposing macrophages to saturated fatty acids (SFA), and endoplasmic reticulum (ER) stress responses essentially contri...

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Detalles Bibliográficos
Autores principales:	Boß, Marcel, Newbatt, Yvette, Gupta, Sahil, Collins, Ian, Brüne, Bernhard, Namgaladze, Dmitry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999824/ https://www.ncbi.nlm.nih.gov/pubmed/27562249 http://dx.doi.org/10.1038/srep32111

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