Targeting DNA Replication Stress for Cancer Therapy

The human cellular genome is under constant stress from extrinsic and intrinsic factors, which can lead to DNA damage and defective replication. In normal cells, DNA damage response (DDR) mediated by various checkpoints will either activate the DNA repair system or induce cellular apoptosis/senescen...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jun, Dai, Qun, Park, Dongkyoo, Deng, Xingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999839/
https://www.ncbi.nlm.nih.gov/pubmed/27548226
http://dx.doi.org/10.3390/genes7080051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999839/
https://www.ncbi.nlm.nih.gov/pubmed/27548226
http://dx.doi.org/10.3390/genes7080051

Ejemplares similares