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Selective Membrane Redistribution and Depletion of Gα(q)-Protein by Pasteurella multocida Toxin

Pasteurella multocida toxin (PMT), the major virulence factor responsible for zoonotic atrophic rhinitis, is a protein deamidase that activates the alpha subunit of heterotrimeric G proteins. Initial activation of G alpha-q-coupled phospholipase C-beta-1 signaling by PMT is followed by uncoupling of...

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Detalles Bibliográficos
Autores principales:	Clemons, Nathan C., Luo, Shuhong, Ho, Mengfei, Wilson, Brenda A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999849/ https://www.ncbi.nlm.nih.gov/pubmed/27490568 http://dx.doi.org/10.3390/toxins8080233

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