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Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers

Mycotoxin contamination threatens health and life of humans and animals throughout the food supply chains. Many of the mycotoxins have been proven to be carcinogens, teratogens and mutagens. The reliable and sensitive sensing methods are requested to monitor mycotoxin contamination. Advanced sensors...

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Detalles Bibliográficos
Autores principales: Xu, Lin, Zhang, Zhaowei, Zhang, Qi, Li, Peiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999855/
https://www.ncbi.nlm.nih.gov/pubmed/27529281
http://dx.doi.org/10.3390/toxins8080239
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author Xu, Lin
Zhang, Zhaowei
Zhang, Qi
Li, Peiwu
author_facet Xu, Lin
Zhang, Zhaowei
Zhang, Qi
Li, Peiwu
author_sort Xu, Lin
collection PubMed
description Mycotoxin contamination threatens health and life of humans and animals throughout the food supply chains. Many of the mycotoxins have been proven to be carcinogens, teratogens and mutagens. The reliable and sensitive sensing methods are requested to monitor mycotoxin contamination. Advanced sensors based on antibodies or aptamers boast the advantages of high sensitivity and rapidity, and have been used in the mycotoxin sensing. These sensors are miniaturized, thereby lowering costs, and are applicable to high-throughput modes. In this work, the latest developments in sensing strategies for mycotoxin determination were critically discussed. Optical and electrochemical sensing modes were compared. The sensing methods for single mycotoxin or multiple mycotoxins in food samples were reviewed, along with the challenges and the future of antibody or aptamer-based sensors. This work might promote academic studies and industrial applications for mycotoxin sensing.
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spelling pubmed-49998552016-09-01 Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers Xu, Lin Zhang, Zhaowei Zhang, Qi Li, Peiwu Toxins (Basel) Review Mycotoxin contamination threatens health and life of humans and animals throughout the food supply chains. Many of the mycotoxins have been proven to be carcinogens, teratogens and mutagens. The reliable and sensitive sensing methods are requested to monitor mycotoxin contamination. Advanced sensors based on antibodies or aptamers boast the advantages of high sensitivity and rapidity, and have been used in the mycotoxin sensing. These sensors are miniaturized, thereby lowering costs, and are applicable to high-throughput modes. In this work, the latest developments in sensing strategies for mycotoxin determination were critically discussed. Optical and electrochemical sensing modes were compared. The sensing methods for single mycotoxin or multiple mycotoxins in food samples were reviewed, along with the challenges and the future of antibody or aptamer-based sensors. This work might promote academic studies and industrial applications for mycotoxin sensing. MDPI 2016-08-12 /pmc/articles/PMC4999855/ /pubmed/27529281 http://dx.doi.org/10.3390/toxins8080239 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Xu, Lin
Zhang, Zhaowei
Zhang, Qi
Li, Peiwu
Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers
title Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers
title_full Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers
title_fullStr Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers
title_full_unstemmed Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers
title_short Mycotoxin Determination in Foods Using Advanced Sensors Based on Antibodies or Aptamers
title_sort mycotoxin determination in foods using advanced sensors based on antibodies or aptamers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999855/
https://www.ncbi.nlm.nih.gov/pubmed/27529281
http://dx.doi.org/10.3390/toxins8080239
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