Cargando…

A Simple Luminescent Adenylate-Cyclase Functional Assay for Evaluation of Bacillus anthracis Edema Factor Activity

Edema Factor (EF), the toxic sub-unit of the Bacillus anthracis Edema Toxin (ET) is a calmodulin-dependent adenylate cyclase whose detrimental activity in the infected host results in severe edema. EF is therefore a major virulence factor of B. anthracis. We describe a simple, rapid and reliable fun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Israeli, Ma’ayan, Rotem, Shahar, Elia, Uri, Bar-Haim, Erez, Cohen, Ofer, Chitlaru, Theodor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999859/ https://www.ncbi.nlm.nih.gov/pubmed/27548219 http://dx.doi.org/10.3390/toxins8080243

Ejemplares similares

Next-Generation Bacillus anthracis Live Attenuated Spore Vaccine Based on the htrA(-) (High Temperature Requirement A) Sterne Strain
por: Chitlaru, Theodor, et al.
Publicado: (2016)

Distinct Contribution of the HtrA Protease and PDZ Domains to Its Function in Stress Resilience and Virulence of Bacillus anthracis
por: Israeli, Ma’ayan, et al.
Publicado: (2019)

Comparative Analysis of the Global Transcriptomic Response to Oxidative Stress of Bacillus anthracis htrA-Disrupted and Parental Wild Type Strains
por: Zaide, Galia, et al.
Publicado: (2020)

Transcriptome Sequencing Data of Bacillus anthracis Vollum ΔhtrA and Its Parental Strain, Isolated under Oxidative Stress
por: Chitlaru, Theodor, et al.
Publicado: (2020)

Early Diagnosis of Pathogen Infection by Cell-Based Activation Immunoassay
por: Bar-Haim, Erez, et al.
Publicado: (2019)

A Novel Approach to Vaccine Development: Concomitant Pathogen Inactivation and Host Immune Stimulation by Peroxynitrite
por: Rotem, Shahar, et al.
Publicado: (2022)

T Cell Response following Anti-COVID-19 BNT162b2 Vaccination Is Maintained against the SARS-CoV-2 Omicron B.1.1.529 Variant of Concern
por: Cohen, Hila, et al.
Publicado: (2022)

Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci
por: Cohen-Gihon, Inbar, et al.
Publicado: (2014)

Draft Genome Sequence of a Rare Israeli Clinical Isolate of Burkholderia pseudomallei
por: Israeli, Ofir, et al.
Publicado: (2019)

Correction for Israeli et al., “Draft Genome Sequence of a Rare Israeli Clinical Isolate of Burkholderia pseudomallei”
por: Israeli, Ofir, et al.
Publicado: (2019)

Implementation of Adenovirus-Mediated Pulmonary Expression of Human ACE2 in HLA Transgenic Mice Enables Establishment of a COVID-19 Murine Model for Assessment of Immune Responses to SARS-CoV-2 Infection
por: Chitlaru, Theodor, et al.
Publicado: (2021)

Transcriptome Sequencing Data Sets of Human Lung Epithelial Cells in the Course of Francisella tularensis Infection
por: Bercovich-Kinori, Adi, et al.
Publicado: (2020)

Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes
por: Arumugham, Vijay B., et al.
Publicado: (2018)

Effects of 39 Compounds on Calmodulin-Regulated Adenylyl Cyclases AC1 and Bacillus anthracis Edema Factor
por: Lübker, Carolin, et al.
Publicado: (2015)

The Adenylate Cyclase Toxins of Bacillus anthracis and Bordetella pertussis Promote Th2 Cell Development by Shaping T Cell Antigen Receptor Signaling
por: Rossi Paccani, Silvia, et al.
Publicado: (2009)

Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2
por: Israeli, Ma’ayan, et al.
Publicado: (2022)

Evaluation of the European Committee on Antimicrobial Susceptibility Testing Guidelines for Rapid Antimicrobial Susceptibility Testing of Bacillus anthracis-, Yersinia pestis- and Francisella tularensis-Positive Blood Cultures
por: Shifman, Ohad, et al.
Publicado: (2021)

Bordetella Adenylate Cyclase-Hemolysin Toxins
por: Guiso, Nicole
Publicado: (2017)

Whole-Genome Immunoinformatic Analysis of F. tularensis: Predicted CTL Epitopes Clustered in Hotspots Are Prone to Elicit a T-Cell Response
por: Zvi, Anat, et al.
Publicado: (2011)

Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8(+) T Cell Epitopes
por: Rotem, Shahar, et al.
Publicado: (2014)

Identification of sea urchin sperm adenylate cyclase
Publicado: (1990)

Pituitary adenylate cyclase activating polypeptide and migraine
por: Zagami, Alessandro S, et al.
Publicado: (2014)

Pathology of wild-type and toxin-independent Bacillus anthracis meningitis in rabbits
por: Sittner, Assa, et al.
Publicado: (2017)

Bacillus anthracis Edema Factor Substrate Specificity: Evidence for New Modes of Action
por: Göttle, Martin, et al.
Publicado: (2012)

Nociceptive Sensory Neurons Mediate Inflammation Induced by Bacillus Anthracis Edema Toxin
por: Yang, Nicole J., et al.
Publicado: (2021)

Toxin-Independent Virulence of Bacillus anthracis in Rabbits
por: Levy, Haim, et al.
Publicado: (2014)

The adenylate cyclase receptor complex and aqueous humor formation.
por: Caprioli, J., et al.
Publicado: (1984)

Protein kinase C sensitizes olfactory adenylate cyclase
Publicado: (1993)

An Introduction to the Toxins Special Issue on the Adenylate Cyclase Toxin
por: Chenal, Alexandre
Publicado: (2018)

Adenylate Cyclase Toxin Tinkering With Monocyte-Macrophage Differentiation
por: Ahmad, Jawid Nazir, et al.
Publicado: (2020)

Pituitary Adenylate Cyclase-Activating Polypeptide in Learning and Memory
por: Gilmartin, Marieke R., et al.
Publicado: (2021)

CRISPR Interference of Adenylate Cyclases from Mycobacterium tuberculosis
por: Nadolinskaia, N. I., et al.
Publicado: (2021)

Anthrax, but Not Bacillus anthracis?
por: Okinaka, Richard, et al.
Publicado: (2006)

Pyrosequencing Bacillus anthracis
por: Wahab, Tara, et al.
Publicado: (2005)

Etymologia: Bacillus anthracis
Publicado: (2014)

Using old antibiotics to treat ancient bacterium—β-lactams for Bacillus anthracis meningitis
por: Sittner, Assa, et al.
Publicado: (2020)

Adenyl cyclases and cAMP in plant signaling - past and present
por: Gehring, Chris
Publicado: (2010)

Adenylate-cyclase activity in platelets of patients with obsessive-compulsive disorder
por: Marazziti, D, et al.
Publicado: (2009)

Functional Dissection of Adenylate Cyclase R, an Inducer of Spore Encapsulation
por: Chen, Zhi-hui, et al.
Publicado: (2010)

Identification of a haem domain in human soluble adenylate cyclase
por: Middelhaufe, Sabine, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jo2l5h8rc2f16o3glv4nqneb29