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Computational analysis of translational readthrough proteins in Drosophila and yeast reveals parallels to alternative splicing

In translational readthrough (TR) the ribosome continues extending the nascent protein beyond the first in-frame termination codon. Due to the lack of dedicated analyses of eukaryotic TR cases, the associated functional-evolutionary advantages are still unclear. Here, based on a variety of computati...

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Detalles Bibliográficos
Autores principales: Pancsa, Rita, Macossay-Castillo, Mauricio, Kosol, Simone, Tompa, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999894/
https://www.ncbi.nlm.nih.gov/pubmed/27561673
http://dx.doi.org/10.1038/srep32142