Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells

Sinularin is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigated the effects of sinularin on two human gastric cancer cell lines, AGS and NCI-N87. Our results demonstrated that sinularin suppressed the proliferation of gastric cancer cells in...

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Detalles Bibliográficos
Autores principales: Wu, Yu-Jen, Wong, Bing-Sang, Yea, Shu-Hao, Lu, Chi-I, Weng, Shun-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999903/
https://www.ncbi.nlm.nih.gov/pubmed/27472346
http://dx.doi.org/10.3390/md14080142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999903/
https://www.ncbi.nlm.nih.gov/pubmed/27472346
http://dx.doi.org/10.3390/md14080142

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