Cargando…
Fucoidans in Nanomedicine
Fucoidans are widespread cost-effective sulfated marine polysaccharides which have raised interest in the scientific community over last decades for their wide spectrum of bioactivities. Unsurprisingly, nanomedicine has grasped these compounds to develop innovative therapeutic and diagnostic nanosys...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999906/ https://www.ncbi.nlm.nih.gov/pubmed/27483292 http://dx.doi.org/10.3390/md14080145 |
_version_ | 1782450186077863936 |
---|---|
author | Chollet, Lucas Saboural, Pierre Chauvierre, Cédric Villemin, Jean-Noël Letourneur, Didier Chaubet, Frédéric |
author_facet | Chollet, Lucas Saboural, Pierre Chauvierre, Cédric Villemin, Jean-Noël Letourneur, Didier Chaubet, Frédéric |
author_sort | Chollet, Lucas |
collection | PubMed |
description | Fucoidans are widespread cost-effective sulfated marine polysaccharides which have raised interest in the scientific community over last decades for their wide spectrum of bioactivities. Unsurprisingly, nanomedicine has grasped these compounds to develop innovative therapeutic and diagnostic nanosystems. The applications of fucoidans in nanomedicine as imaging agents, drug carriers or for their intrinsic properties are reviewed here after a short presentation of the main structural data and biological properties of fucoidans. The origin and the physicochemical specifications of fucoidans are summarized in order to discuss the strategy of fucoidan-containing nanosystems in Human health. Currently, there is a need for reproducible, well characterized fucoidan fractions to ensure significant progress. |
format | Online Article Text |
id | pubmed-4999906 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-49999062016-09-01 Fucoidans in Nanomedicine Chollet, Lucas Saboural, Pierre Chauvierre, Cédric Villemin, Jean-Noël Letourneur, Didier Chaubet, Frédéric Mar Drugs Review Fucoidans are widespread cost-effective sulfated marine polysaccharides which have raised interest in the scientific community over last decades for their wide spectrum of bioactivities. Unsurprisingly, nanomedicine has grasped these compounds to develop innovative therapeutic and diagnostic nanosystems. The applications of fucoidans in nanomedicine as imaging agents, drug carriers or for their intrinsic properties are reviewed here after a short presentation of the main structural data and biological properties of fucoidans. The origin and the physicochemical specifications of fucoidans are summarized in order to discuss the strategy of fucoidan-containing nanosystems in Human health. Currently, there is a need for reproducible, well characterized fucoidan fractions to ensure significant progress. MDPI 2016-07-29 /pmc/articles/PMC4999906/ /pubmed/27483292 http://dx.doi.org/10.3390/md14080145 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Chollet, Lucas Saboural, Pierre Chauvierre, Cédric Villemin, Jean-Noël Letourneur, Didier Chaubet, Frédéric Fucoidans in Nanomedicine |
title | Fucoidans in Nanomedicine |
title_full | Fucoidans in Nanomedicine |
title_fullStr | Fucoidans in Nanomedicine |
title_full_unstemmed | Fucoidans in Nanomedicine |
title_short | Fucoidans in Nanomedicine |
title_sort | fucoidans in nanomedicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999906/ https://www.ncbi.nlm.nih.gov/pubmed/27483292 http://dx.doi.org/10.3390/md14080145 |
work_keys_str_mv | AT cholletlucas fucoidansinnanomedicine AT sabouralpierre fucoidansinnanomedicine AT chauvierrecedric fucoidansinnanomedicine AT villeminjeannoel fucoidansinnanomedicine AT letourneurdidier fucoidansinnanomedicine AT chaubetfrederic fucoidansinnanomedicine |