Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells

[Image: see text] Mammalian target of rapamycin (mTOR) signaling is a core pathway in cellular metabolism, and control of the mTOR pathway by rapamycin shows potential for the treatment of metabolic diseases. In this study, we employed a new proximity biotin-labeling method using promiscuous biotin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Song-Yi, Lee, Hakbong, Lee, Hye-Kyeong, Lee, Seung-Won, Ha, Sung Chul, Kwon, Taejoon, Seo, Jeong Kon, Lee, Changwook, Rhee, Hyun-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999972/
https://www.ncbi.nlm.nih.gov/pubmed/27610411
http://dx.doi.org/10.1021/acscentsci.6b00137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999972/
https://www.ncbi.nlm.nih.gov/pubmed/27610411
http://dx.doi.org/10.1021/acscentsci.6b00137

Ejemplares similares