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Codon optimization of antigen coding sequences improves the immune potential of DNA vaccines against avian influenza virus H5N1 in mice and chickens

BACKGROUND: Highly pathogenic avian influenza viruses are a serious threat to domestic poultry and can be a source of new human pandemic and annual influenza strains. Vaccination is the main strategy of protection against influenza, thus new generation vaccines, including DNA vaccines, are needed. O...

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Detalles Bibliográficos
Autores principales:	Stachyra, Anna, Redkiewicz, Patrycja, Kosson, Piotr, Protasiuk, Anna, Góra-Sochacka, Anna, Kudla, Grzegorz, Sirko, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000471/ https://www.ncbi.nlm.nih.gov/pubmed/27562235 http://dx.doi.org/10.1186/s12985-016-0599-y

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