The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress

BACKGROUND: The intestinal epithelium plays a critical role in nutrient absorption and innate immune defense. Recent studies showed that metabolic stress pathways, in particular the integrated stress response (ISR), control intestinal epithelial cell fate and function. Here, we used RNA-seq to analy...

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Detalles Bibliográficos
Autores principales: Tsalikis, Jessica, Pan, Qun, Tattoli, Ivan, Maisonneuve, Charles, Blencowe, Benjamin J., Philpott, Dana J., Girardin, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000506/
https://www.ncbi.nlm.nih.gov/pubmed/27561422
http://dx.doi.org/10.1186/s12864-016-2999-1

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