Type-1 angiotensin receptor signaling in central nervous system myeloid cells is pathogenic during fatal alphavirus encephalitis in mice

BACKGROUND: Alphaviruses can cause fatal encephalitis in humans. Natural infections occur via the bite of infected mosquitos, but aerosol transmissibility makes some of these viruses potential bioterrorism agents. Central nervous system (CNS) host responses contribute to alphavirus pathogenesis in e...

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Detalles Bibliográficos
Autores principales: Blakely, Pennelope K., Huber, Amanda K., Irani, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000512/
https://www.ncbi.nlm.nih.gov/pubmed/27562117
http://dx.doi.org/10.1186/s12974-016-0683-7

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