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Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions

PURPOSE: To evaluate the role of fine needle aspiration (FNAC) as a diagnostic tool in cases of orbital and ocular adnexal masses. Cytological findings were correlated with histopathological diagnosis wherever possible. METHODS: FNAC was performed in 29 patients of different age groups presenting wi...

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Detalles Bibliográficos
Autores principales: Khan, Lubna, Malukani, Kamal, Malaiya, Siddharth, Yeshwante, Prashant, Ishrat, Saba, Nandedkar, Shirish S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000532/
https://www.ncbi.nlm.nih.gov/pubmed/27621787
http://dx.doi.org/10.4103/2008-322X.188397
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author Khan, Lubna
Malukani, Kamal
Malaiya, Siddharth
Yeshwante, Prashant
Ishrat, Saba
Nandedkar, Shirish S.
author_facet Khan, Lubna
Malukani, Kamal
Malaiya, Siddharth
Yeshwante, Prashant
Ishrat, Saba
Nandedkar, Shirish S.
author_sort Khan, Lubna
collection PubMed
description PURPOSE: To evaluate the role of fine needle aspiration (FNAC) as a diagnostic tool in cases of orbital and ocular adnexal masses. Cytological findings were correlated with histopathological diagnosis wherever possible. METHODS: FNAC was performed in 29 patients of different age groups presenting with orbital and ocular adnexal masses. Patients were evaluated clinically and investigated by non-invasive techniques before fine needle aspiration of the masses. Smears were analyzed by a cytologist in all cases. Further, results of cytology were compared with the histopathological diagnosis. RESULTS: The age of patients ranged from 1 to 68 years (mean: 29.79±19.29). There were 14 males and 15 females with a male to female ratio of 0.93:1. Out of 29 cases, 26 aspirates were cellular. Cellularity was insufficient in three (10.34%) aspirates. Out of 26 cellular aspirates, 11 were non-neoplastic while 15 were neoplastic on cytology. Subsequent histopathologic examination was done in 21/26 cases. Concordance rate of FNAC in orbital and ocular adnexal mass lesions with respect to the precise histologic diagnosis was 90%. CONCLUSION: When properly used in well-indicated patients (in cases where a diagnosis cannot be made by clinical and imaging findings alone), FNAC of orbital and periorbital lesions is an invaluable and suitable adjunct diagnostic technique that necessitates close cooperation between the ophthalmologist and cytologist. However, nondiagnostic aspirates may sometimes be obtained, and an inconclusive FNAC should not always be ignored.
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spelling pubmed-50005322016-09-12 Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions Khan, Lubna Malukani, Kamal Malaiya, Siddharth Yeshwante, Prashant Ishrat, Saba Nandedkar, Shirish S. J Ophthalmic Vis Res Original Article PURPOSE: To evaluate the role of fine needle aspiration (FNAC) as a diagnostic tool in cases of orbital and ocular adnexal masses. Cytological findings were correlated with histopathological diagnosis wherever possible. METHODS: FNAC was performed in 29 patients of different age groups presenting with orbital and ocular adnexal masses. Patients were evaluated clinically and investigated by non-invasive techniques before fine needle aspiration of the masses. Smears were analyzed by a cytologist in all cases. Further, results of cytology were compared with the histopathological diagnosis. RESULTS: The age of patients ranged from 1 to 68 years (mean: 29.79±19.29). There were 14 males and 15 females with a male to female ratio of 0.93:1. Out of 29 cases, 26 aspirates were cellular. Cellularity was insufficient in three (10.34%) aspirates. Out of 26 cellular aspirates, 11 were non-neoplastic while 15 were neoplastic on cytology. Subsequent histopathologic examination was done in 21/26 cases. Concordance rate of FNAC in orbital and ocular adnexal mass lesions with respect to the precise histologic diagnosis was 90%. CONCLUSION: When properly used in well-indicated patients (in cases where a diagnosis cannot be made by clinical and imaging findings alone), FNAC of orbital and periorbital lesions is an invaluable and suitable adjunct diagnostic technique that necessitates close cooperation between the ophthalmologist and cytologist. However, nondiagnostic aspirates may sometimes be obtained, and an inconclusive FNAC should not always be ignored. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5000532/ /pubmed/27621787 http://dx.doi.org/10.4103/2008-322X.188397 Text en Copyright: © 2016 Journal of Ophthalmic and Vision Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Khan, Lubna
Malukani, Kamal
Malaiya, Siddharth
Yeshwante, Prashant
Ishrat, Saba
Nandedkar, Shirish S.
Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions
title Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions
title_full Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions
title_fullStr Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions
title_full_unstemmed Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions
title_short Role of Fine Needle Aspiration Cytology as a Diagnostic Tool in Orbital and Adnexal Lesions
title_sort role of fine needle aspiration cytology as a diagnostic tool in orbital and adnexal lesions
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000532/
https://www.ncbi.nlm.nih.gov/pubmed/27621787
http://dx.doi.org/10.4103/2008-322X.188397
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