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Evidence for biased agonists and antagonists at the endothelin receptors
Biased ligands represent a new strategy for the development of more effective and better tolerated drugs. To date there has been a paucity of research exploring the potential of ligands that exhibit either G protein or β-arrestin pathway selectivity at the endothelin receptors. Re-analysis of data m...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000545/ https://www.ncbi.nlm.nih.gov/pubmed/26898124 http://dx.doi.org/10.1016/j.lfs.2016.02.069 |