Theophylline-Based KMUP-1 Improves Steatohepatitis via MMP-9/IL-10 and Lipolysis via HSL/p-HSL in Obese Mice

KMUP-1 (7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) has been reported to cause hepatic fat loss. However, the action mechanisms of KMUP-1 in obesity-induced steatohepatitis remains unclear. This study elucidated the steatohepatitis via matrix metallopeptidase 9 (MMP-9) and tumo...

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Detalles Bibliográficos
Autores principales: Wu, Bin-Nan, Kuo, Kung-Kai, Chen, Yu-Hsun, Chang, Chain-Ting, Huang, Hung-Tu, Chai, Chee-Yin, Dai, Zen-Kong, Chen, Ing-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000741/
https://www.ncbi.nlm.nih.gov/pubmed/27548140
http://dx.doi.org/10.3390/ijms17081345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000741/
https://www.ncbi.nlm.nih.gov/pubmed/27548140
http://dx.doi.org/10.3390/ijms17081345

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