Cargando…

Tamoxifen Resistance: Emerging Molecular Targets

17β-Estradiol (E2) plays a pivotal role in the development and progression of breast cancer. As a result, blockade of the E2 signal through either tamoxifen (TAM) or aromatase inhibitors is an important therapeutic strategy to treat or prevent estrogen receptor (ER) positive breast cancer. However,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rondón-Lagos, Milena, Villegas, Victoria E., Rangel, Nelson, Sánchez, Magda Carolina, Zaphiropoulos, Peter G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000752/ https://www.ncbi.nlm.nih.gov/pubmed/27548161 http://dx.doi.org/10.3390/ijms17081357

Ejemplares similares

Tamoxifen Treatment of Breast Cancer Cells: Impact on Hedgehog/GLI1 Signaling
por: Villegas, Victoria E., et al.
Publicado: (2016)

Profiling of gene expression regulated by 17β-estradiol and tamoxifen in estrogen receptor-positive and estrogen receptor-negative human breast cancer cell lines
por: Rangel, Nelson, et al.
Publicado: (2017)

Obesity and Androgen Receptor Signaling: Associations and Potential Crosstalk in Breast Cancer Cells
por: Rangel, Nelson, et al.
Publicado: (2021)

Effect of low doses of estradiol and tamoxifen on breast cancer cell karyotypes
por: Rondón-Lagos, Milena, et al.
Publicado: (2016)

Intrinsic Subtypes and Androgen Receptor Gene Expression in Primary Breast Cancer. A Meta-Analysis
por: Cruz-Tapias, Paola, et al.
Publicado: (2021)

Resistance and Overcoming Resistance in Breast Cancer
por: Luque-Bolivar, Andrea, et al.
Publicado: (2020)

The Role of Chromosomal Instability in Cancer and Therapeutic Responses
por: Vargas-Rondón, Natalia, et al.
Publicado: (2017)

Analyzing biological and molecular characteristics and genomic damage induced by exposure to asbestos
por: Ospina, Diana, et al.
Publicado: (2019)

Role of chromosomal instability and clonal heterogeneity in the therapy response of breast cancer cell lines
por: Vargas-Rondón, Natalia, et al.
Publicado: (2020)

New Insights in the Cytogenetic Practice: Karyotypic Chaos, Non-Clonal Chromosomal Alterations and Chromosomal Instability in Human Cancer and Therapy Response
por: Rangel, Nelson, et al.
Publicado: (2017)

Neighboring Gene Regulation by Antisense Long Non-Coding RNAs
por: Villegas, Victoria E., et al.
Publicado: (2015)

High chromosomal instability in workers occupationally exposed to solvents and paint removers
por: Villalba-Campos, Mónica, et al.
Publicado: (2016)

Chromosomal Instability as Enabling Feature and Central Hallmark of Breast Cancer
por: Castellanos, Giovanny, et al.
Publicado: (2023)

Molecular prediction of tamoxifen resistance in breast cancer
por: Kok, M, et al.
Publicado: (2005)

Molecular mechanisms and mode of tamoxifen resistance in breast cancer
por: Ali, Shazia, et al.
Publicado: (2016)

AR/ER Ratio Correlates with Expression of Proliferation Markers and with Distinct Subset of Breast Tumors
por: Rangel, Nelson, et al.
Publicado: (2020)

Tamoxifen non-estrogen receptor mediated molecular targets
por: Bogush, Tatiana, et al.
Publicado: (2012)

Identification and targeting of selective vulnerability rendered by tamoxifen resistance
por: Singh, Madhurendra, et al.
Publicado: (2020)

Profile of Chromosomal Alterations, Chromosomal Instability and Clonal Heterogeneity in Colombian Farmers Exposed to Pesticides
por: Meléndez-Flórez, María Paula, et al.
Publicado: (2022)

Unraveling the chromosome 17 patterns of FISH in interphase nuclei: an in-depth analysis of the HER2 amplicon and chromosome 17 centromere by karyotyping, FISH and M-FISH in breast cancer cells
por: Rondón-Lagos, Milena, et al.
Publicado: (2014)

Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer
por: Tiwary, Richa, et al.
Publicado: (2011)

Resuming Sensitivity of Tamoxifen-Resistant Breast Cancer Cells to Tamoxifen by Tetrandrine
por: Wang, Yuntao, et al.
Publicado: (2021)

The impact of S6K1 kinase on neuroblastoma cell proliferation is independent of GLI1 signaling
por: Diao, Yumei, et al.
Publicado: (2014)

Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance
por: Koren, John, et al.
Publicado: (2012)

Tamoxifen Resistance in Breast Cancer
por: Chang, Minsun
Publicado: (2012)

MicroRNA-320a sensitizes tamoxifen-resistant breast cancer cells to tamoxifen by targeting ARPP-19 and ERRγ*
por: Lü, Mingrong, et al.
Publicado: (2015)

Quantification of cell-free DNA for evaluating genotoxic damage from occupational exposure to car paints
por: Villalba-Campos, Mónica, et al.
Publicado: (2016)

Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance
por: Koren, John, et al.
Publicado: (2012)

FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations
por: Gambella, Alessandro, et al.
Publicado: (2023)

Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells
por: Moon, Seo Yun, et al.
Publicado: (2021)

Tamoxifen resistance and adjuvant hormone therapy
por: Howell, A
Publicado: (2005)

Leishmania is not prone to develop resistance to tamoxifen
por: Coelho, Adriano C., et al.
Publicado: (2015)

Tamoxifen side effects: pharmacogenetic and clinical approach in Mexican mestizos
por: Rangel-Méndez, Jorge-Aarón, et al.
Publicado: (2019)

Trans-splicing in Higher Eukaryotes: Implications for Cancer Development?
por: Zaphiropoulos, Peter G.
Publicado: (2011)

Genetic variations and alternative splicing: the Glioma associated oncogene 1, GLI1
por: Zaphiropoulos, Peter G.
Publicado: (2012)

Targeting Ribosome Biogenesis to Combat Tamoxifen Resistance in ER+ve Breast Cancer
por: Tsoi, Ho, et al.
Publicado: (2022)

Identification of potential target genes of honokiol in overcoming breast cancer resistance to tamoxifen
por: Hermawan, Adam, et al.
Publicado: (2022)

Oxidative stress contributes to the tamoxifen-induced killing of breast cancer cells: implications for tamoxifen therapy and resistance
por: Bekele, Raie T., et al.
Publicado: (2016)

Molecular Action of Tamoxifen in the Ovaries of Rats with Mammary Neoplasia
por: Nynca, Anna, et al.
Publicado: (2023)

Interaction of tamoxifen with the multidrug resistance P-glycoprotein.
por: Callaghan, R., et al.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_ghv6o2vq6kfif2lu2fi3l2vmae