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Inflammatory Cutaneous Diseases in Renal Transplant Recipients
Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000757/ https://www.ncbi.nlm.nih.gov/pubmed/27548160 http://dx.doi.org/10.3390/ijms17081362 |
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author | Savoia, Paola Cavaliere, Giovanni Zavattaro, Elisa Veronese, Federica Fava, Paolo |
author_facet | Savoia, Paola Cavaliere, Giovanni Zavattaro, Elisa Veronese, Federica Fava, Paolo |
author_sort | Savoia, Paola |
collection | PubMed |
description | Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relative incidence and characteristics of inflammatory skin diseases in this type of patient. In this study, we analyze the incidence of a number of inflammatory cutaneous diseases in a cohort of patients who underwent kidney transplantation. Although our study shows a relatively low incidence of these pathologies in transplanted patients—in agreement with the general action of immunosuppressant therapies in reducing inflammation—we scored a different efficacy of the various immunosuppressive regimens on inflammatory and autoimmune skin diseases. This information can be key for designing immunosuppressive regimens and devising accurate follow-up protocols. |
format | Online Article Text |
id | pubmed-5000757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-50007572016-09-01 Inflammatory Cutaneous Diseases in Renal Transplant Recipients Savoia, Paola Cavaliere, Giovanni Zavattaro, Elisa Veronese, Federica Fava, Paolo Int J Mol Sci Article Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relative incidence and characteristics of inflammatory skin diseases in this type of patient. In this study, we analyze the incidence of a number of inflammatory cutaneous diseases in a cohort of patients who underwent kidney transplantation. Although our study shows a relatively low incidence of these pathologies in transplanted patients—in agreement with the general action of immunosuppressant therapies in reducing inflammation—we scored a different efficacy of the various immunosuppressive regimens on inflammatory and autoimmune skin diseases. This information can be key for designing immunosuppressive regimens and devising accurate follow-up protocols. MDPI 2016-08-19 /pmc/articles/PMC5000757/ /pubmed/27548160 http://dx.doi.org/10.3390/ijms17081362 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Savoia, Paola Cavaliere, Giovanni Zavattaro, Elisa Veronese, Federica Fava, Paolo Inflammatory Cutaneous Diseases in Renal Transplant Recipients |
title | Inflammatory Cutaneous Diseases in Renal Transplant Recipients |
title_full | Inflammatory Cutaneous Diseases in Renal Transplant Recipients |
title_fullStr | Inflammatory Cutaneous Diseases in Renal Transplant Recipients |
title_full_unstemmed | Inflammatory Cutaneous Diseases in Renal Transplant Recipients |
title_short | Inflammatory Cutaneous Diseases in Renal Transplant Recipients |
title_sort | inflammatory cutaneous diseases in renal transplant recipients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000757/ https://www.ncbi.nlm.nih.gov/pubmed/27548160 http://dx.doi.org/10.3390/ijms17081362 |
work_keys_str_mv | AT savoiapaola inflammatorycutaneousdiseasesinrenaltransplantrecipients AT cavalieregiovanni inflammatorycutaneousdiseasesinrenaltransplantrecipients AT zavattaroelisa inflammatorycutaneousdiseasesinrenaltransplantrecipients AT veronesefederica inflammatorycutaneousdiseasesinrenaltransplantrecipients AT favapaolo inflammatorycutaneousdiseasesinrenaltransplantrecipients |