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Inflammatory Cutaneous Diseases in Renal Transplant Recipients

Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relat...

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Autores principales: Savoia, Paola, Cavaliere, Giovanni, Zavattaro, Elisa, Veronese, Federica, Fava, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000757/
https://www.ncbi.nlm.nih.gov/pubmed/27548160
http://dx.doi.org/10.3390/ijms17081362
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author Savoia, Paola
Cavaliere, Giovanni
Zavattaro, Elisa
Veronese, Federica
Fava, Paolo
author_facet Savoia, Paola
Cavaliere, Giovanni
Zavattaro, Elisa
Veronese, Federica
Fava, Paolo
author_sort Savoia, Paola
collection PubMed
description Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relative incidence and characteristics of inflammatory skin diseases in this type of patient. In this study, we analyze the incidence of a number of inflammatory cutaneous diseases in a cohort of patients who underwent kidney transplantation. Although our study shows a relatively low incidence of these pathologies in transplanted patients—in agreement with the general action of immunosuppressant therapies in reducing inflammation—we scored a different efficacy of the various immunosuppressive regimens on inflammatory and autoimmune skin diseases. This information can be key for designing immunosuppressive regimens and devising accurate follow-up protocols.
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spelling pubmed-50007572016-09-01 Inflammatory Cutaneous Diseases in Renal Transplant Recipients Savoia, Paola Cavaliere, Giovanni Zavattaro, Elisa Veronese, Federica Fava, Paolo Int J Mol Sci Article Kidney transplant recipients frequently suffer from skin infections and malignancies, possibly due to the effects of long-term immunosuppressive therapy. While the relationships between immunosuppression and these pathological conditions have been widely investigated, little is known about the relative incidence and characteristics of inflammatory skin diseases in this type of patient. In this study, we analyze the incidence of a number of inflammatory cutaneous diseases in a cohort of patients who underwent kidney transplantation. Although our study shows a relatively low incidence of these pathologies in transplanted patients—in agreement with the general action of immunosuppressant therapies in reducing inflammation—we scored a different efficacy of the various immunosuppressive regimens on inflammatory and autoimmune skin diseases. This information can be key for designing immunosuppressive regimens and devising accurate follow-up protocols. MDPI 2016-08-19 /pmc/articles/PMC5000757/ /pubmed/27548160 http://dx.doi.org/10.3390/ijms17081362 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Savoia, Paola
Cavaliere, Giovanni
Zavattaro, Elisa
Veronese, Federica
Fava, Paolo
Inflammatory Cutaneous Diseases in Renal Transplant Recipients
title Inflammatory Cutaneous Diseases in Renal Transplant Recipients
title_full Inflammatory Cutaneous Diseases in Renal Transplant Recipients
title_fullStr Inflammatory Cutaneous Diseases in Renal Transplant Recipients
title_full_unstemmed Inflammatory Cutaneous Diseases in Renal Transplant Recipients
title_short Inflammatory Cutaneous Diseases in Renal Transplant Recipients
title_sort inflammatory cutaneous diseases in renal transplant recipients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000757/
https://www.ncbi.nlm.nih.gov/pubmed/27548160
http://dx.doi.org/10.3390/ijms17081362
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AT veronesefederica inflammatorycutaneousdiseasesinrenaltransplantrecipients
AT favapaolo inflammatorycutaneousdiseasesinrenaltransplantrecipients