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Prostate-associated gene 4 (PAGE4), an intrinsically disordered cancer/testis antigen, is a novel therapeutic target for prostate cancer

Prostate-associated gene 4 (PAGE4) is a remarkably prostate-specific Cancer/Testis Antigen that is highly upregulated in the human fetal prostate and its diseased states but not in the adult normal gland. PAGE4 is an intrinsically disordered protein (IDP) that functions as a stress-response protein...

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Detalles Bibliográficos
Autores principales: Kulkarni, Prakash, Dunker, A Keith, Weninger, Keith, Orban, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000790/
https://www.ncbi.nlm.nih.gov/pubmed/27270343
http://dx.doi.org/10.4103/1008-682X.181818