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Demethylation treatment restores erectile function in a rat model of hyperhomocysteinemia
Methylation modification is an important cellular mechanism of gene expression regulation. Dimethylarginine dimethylaminohydrolase-2 (DDAH-2) protein is a pivotal molecular for endothelium function. To explore the effects of 5-aza-deoxycytidine (5-aza), a demethylation agent, in hyperhomocysteinemia...
Autores principales: | Zhang, Zheng, Zhu, Lei-Lei, Jiang, He-Song, Chen, Hai, Chen, Yun, Dai, Yu-Tian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000801/ https://www.ncbi.nlm.nih.gov/pubmed/26585696 http://dx.doi.org/10.4103/1008-682X.163271 |
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