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Suppression of spermatogenesis by testosterone undecanoate-loaded injectable in situ-forming implants in adult male rats

We have investigated the feasibility of administration of testosterone undecanoate (TU)-loaded injectable in situ-forming implant (ISFI) for contraception in adult male Sprague–Dawley rats. Male rats were treated with vehicle, TU-loaded ISFIs (540, 270 and 135 mg TU kg(−1)) or TU injections (45 mg T...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Wei, Zhang, Chong, Zhang, Wei, Yang, Dan, Meng, Shu, Wang, Ping, Guo, Jing, Liu, Dan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000806/
https://www.ncbi.nlm.nih.gov/pubmed/26459781
http://dx.doi.org/10.4103/1008-682X.160886

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