Cargando…
A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity
Aberrant mitochondrial fission plays a pivotal role in the pathogenesis of skeletal muscle insulin resistance. However, fusion-fission dynamics are physiologically regulated by inherent tissue-specific and nutrient-sensitive processes that may have distinct or even opposing effects with respect to i...
Autores principales: | Tol, Marc J., Ottenhoff, Roelof, van Eijk, Marco, Zelcer, Noam, Aten, Jan, Houten, Sander M., Geerts, Dirk, van Roomen, Cindy, Bierlaagh, Marlou C., Scheij, Saskia, Hoeksema, Marten A., Aerts, Johannes M., Bogan, Jonathan S., Dorn, Gerald W., Argmann, Carmen A., Verhoeven, Arthur J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001173/ https://www.ncbi.nlm.nih.gov/pubmed/27325287 http://dx.doi.org/10.2337/db16-0243 |
Ejemplares similares
-
Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism
por: Lombardo, Elisa, et al.
Publicado: (2012) -
Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival
por: Gabriel, Tanit L., et al.
Publicado: (2017) -
Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease
por: Marques, André R. A., et al.
Publicado: (2016) -
Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene
por: Cook, Emma C. L., et al.
Publicado: (2017) -
Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation
por: van Eijk, Marco, et al.
Publicado: (2009)