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Detection of high variability in gene expression from single-cell RNA-seq profiling

BACKGROUND: The advancement of the next-generation sequencing technology enables mapping gene expression at the single-cell level, capable of tracking cell heterogeneity and determination of cell subpopulations using single-cell RNA sequencing (scRNA-seq). Unlike the objectives of conventional RNA-s...

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Detalles Bibliográficos
Autores principales: Chen, Hung-I Harry, Jin, Yufang, Huang, Yufei, Chen, Yidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001205/
https://www.ncbi.nlm.nih.gov/pubmed/27556924
http://dx.doi.org/10.1186/s12864-016-2897-6

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